Tissue-specific and reversible RNA interference in transgenic mice.
about
Senescence of activated stellate cells limits liver fibrosisAnimal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What Is under DevelopmentModeling the study of DNA damage responses in miceGenetics in non-genetic model systemsWnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approachesGenetically engineered mouse models in oncology research and cancer medicineReversible suppression of an essential gene in adult mice using transgenic RNA interferenceUBF levels determine the number of active ribosomal RNA genes in mammalsAn inducible RNA interference system for the functional dissection of mouse embryogenesisPrinciples of cancer therapy: oncogene and non-oncogene addictionOrganic small hairpin RNAs (OshR): a do-it-yourself platform for transgene-based gene silencing.Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories.Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivoAn artificial miRNA against HPSE suppresses melanoma invasion properties, correlating with a down-regulation of chemokines and MAPK phosphorylation.Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activityTransgenic, inducible RNAi in megakaryocytes and platelets in mice.RNA interference screening demystified.Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown.Silencing of the mineralocorticoid receptor by ribonucleic acid interference in transgenic rats disrupts endocrine homeostasis.Gene targeting to the stroma of the prostate and bone.Cell- and region-specific miR30-based gene knock-down with temporal control in the rat brainA Pipeline for Drug Target Identification and ValidationReversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference.Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition.Accelerating cancer modeling with RNAi and nongermline genetically engineered mouse models.The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.Rad51 supports triple negative breast cancer metastasis.The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation.Genetically engineered mouse models for drug development and preclinical trials.Lentiviral transgenic microRNA-based shRNA suppressed mouse cytochromosome P450 3A (CYP3A) expression in a dose-dependent and inheritable manner.Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs.PTEN action in leukaemia dictated by the tissue microenvironment.Shortcomings of short hairpin RNA-based transgenic RNA interference in mouse oocytes.Animal models and therapeutic molecular targets of cancer: utility and limitations.Conditional gene expression systems in the transgenic rat brain.Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing.A nanobody-based system using fluorescent proteins as scaffolds for cell-specific gene manipulationA novel piggyBac transposon inducible expression system identifies a role for AKT signalling in primordial germ cell migrationAn RNAi-based approach to down-regulate a gene family in vivo.
P2860
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P2860
Tissue-specific and reversible RNA interference in transgenic mice.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Tissue-specific and reversible RNA interference in transgenic mice.
@ast
Tissue-specific and reversible RNA interference in transgenic mice.
@en
type
label
Tissue-specific and reversible RNA interference in transgenic mice.
@ast
Tissue-specific and reversible RNA interference in transgenic mice.
@en
prefLabel
Tissue-specific and reversible RNA interference in transgenic mice.
@ast
Tissue-specific and reversible RNA interference in transgenic mice.
@en
P2093
P2860
P50
P356
P1433
P1476
Tissue-specific and reversible RNA interference in transgenic mice.
@en
P2093
Lars Zender
Prem K Premsrirut
Scott W Lowe
P2860
P2888
P304
P356
10.1038/NG2045
P407
P50
P577
2007-06-17T00:00:00Z