Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
about
Increase in the 64-kDa subunit of the polyadenylation/cleavage stimulatory factor during the G0 to S phase transitionAccurate 5' splice-site selection in mouse kappa immunoglobulin light chain premessenger RNAs is not cell-type-specificHeterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cellsAlternative poly(A) site selection in complex transcription units: means to an end?Multiple features contribute to the use of the immunoglobulin M secretion-specific poly(A) signal but are not required for developmental regulation.A 6-fold difference in the half-life of immunoglobulin mu heavy chain mRNA in cell lines representing two stages of B cell differentiation.Exon size affects competition between splicing and cleavage-polyadenylation in the immunoglobulin mu geneRegulated immunoglobulin (Ig) RNA processing does not require specific cis-acting sequences: non-Ig RNA can be alternatively processed in B cells and plasma cells.The developmentally regulated shift from membrane to secreted mu mRNA production is accompanied by an increase in cleavage-polyadenylation efficiency but no measurable change in splicing efficiency.Parameters that govern the regulation of immunoglobulin delta heavy-chain gene expression.The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice.Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity.The murine IgM secretory poly(A) site contains dual upstream and downstream elements which affect polyadenylationA secondary structure at the 3' splice site affects the in vitro splicing reaction of mouse immunoglobulin mu chain pre-mRNAs.Repositioning of an alternative exon sequence of mouse IgM pre-mRNA activates splicing of the preceding intron.
P2860
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P2860
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@ast
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@en
type
label
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@ast
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@en
prefLabel
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@ast
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@en
P2093
P2860
P356
P1476
Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA
@en
P2093
N M Avdalovic
N Tsurushita
P2860
P304
P356
10.1093/NAR/15.11.4603
P407
P577
1987-06-01T00:00:00Z