A mechanistic description of gating of the human cardiac ryanodine receptor in a regulated minimal environment.
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Insights into the gating mechanism of the ryanodine-modified human cardiac Ca2+-release channel (ryanodine receptor 2).Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gatingEffect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor.Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity.A missense mutation makes a mess of Ca2+ sensing.Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.
P2860
A mechanistic description of gating of the human cardiac ryanodine receptor in a regulated minimal environment.
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2012 nî lūn-bûn
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name
A mechanistic description of g ...... regulated minimal environment.
@ast
A mechanistic description of g ...... regulated minimal environment.
@en
type
label
A mechanistic description of g ...... regulated minimal environment.
@ast
A mechanistic description of g ...... regulated minimal environment.
@en
prefLabel
A mechanistic description of g ...... regulated minimal environment.
@ast
A mechanistic description of g ...... regulated minimal environment.
@en
P2093
P2860
P356
P1476
A mechanistic description of g ...... regulated minimal environment.
@en
P2093
Alan J Williams
N Lowri Thomas
Saptarshi Mukherjee
P2860
P304
P356
10.1085/JGP.201110706
P577
2012-07-16T00:00:00Z