about
DNA-catalyzed sequence-specific hydrolysis of DNAProtein design: toward functional metalloenzymesIdentification of efficient and sequence specific bimolecular artificial ribonucleases by a combinatorial approach.Anticancer, antioxidant activities, and DNA affinity of novel monocationic bithiophenes and analogues.Mixed ligand copper(II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity.Chemical modification of Ce(IV)/EDTA-based artificial restriction DNA cutter for versatile manipulation of double-stranded DNA.Incorporation of Cobalt-Cyclen Complexes into Templated Nanogels Results in Enhanced Activity.Artificial DNA cutters for DNA manipulation and genome engineering.Palladium(II) Complexes of Biorelevant Ligands. Synthesis, Structures, Cytotoxicity and Rich DNA/HSA Interaction Studies.Heteroleptic arene Ru(II) dipyrrinato complexes: DNA, protein binding and anti-cancer activity against the ACHN cancer cell line.Synthesis, characterization, DNA/BSA interactions and anticancer activity of achiral and chiral copper complexes.Enantiomeric specificity of biologically significant Cu(II) and Zn(II) chromone complexes towards DNA.Potent oxidative DNA cleavage by the di-copper cytotoxin: [Cu2(μ-terephthalate)(1,10-phen)4]2+.DNA binding, nuclease activity and cytotoxicity studies of Cu(II) complexes of tridentate ligands.Nuclease activity via self-activation and anticancer activity of a mononuclear copper(II) complex: novel role of the tertiary butyl group in the ligand frame.Chemical-reaction-based site-selective DNA cutter for PCR-free gene manipulation.Poly[[μ-bis-(4-nitro-phen-yl) phosphato-κ(2) O,O']sodium].Cleavage of double-strand DNA by zinc complexes of dicationic 2,2'-dipyridyl derivatives.On the question of stepwise vs. concerted cleavage of RNA models promoted by a synthetic dinuclear Zn(II) complex in methanol: implementation of a noncleavable phosphonate probe.Copper inverse-9-metallacrown-3 compounds interacting with DNA.Hydrolytic cleavage of DNA-model substrates promoted by polyoxovanadates.Oxidation of an oligonucleotide-bound Ce(III)/multiphosphonate complex for site-selective DNA scission.Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA.When structural and electronic analogy leads to reactivity: the unprecedented phosphodiesterase activity of vanadates.DNA hydrolytic cleavage catalyzed by synthetic multinuclear metallonucleases.Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle.Questioning the paradigm of metal complex promoted phosphodiester hydrolysis: [Mo7O24](6-) polyoxometalate cluster as an unlikely catalyst for the hydrolysis of a DNA model substrate.Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission site and specificity.Trinuclear rare earth metal complexes based on 1,3,5-triamino-1,3,5-trideoxy-cis inositol as catalysts for the hydrolysis of phosphodiesters.Tri- and tetra-substituted cyclen based lanthanide(III) ion complexes as ribonuclease mimics: a study into the effect of log Ka, hydration and hydrophobicity on phosphodiester hydrolysis of the RNA-model 2-hydroxypropyl-4-nitrophenyl phosphate (HPNPTriazolopyridopyrimidines: an emerging family of effective DNA photocleavers. DNA binding. Antileishmanial activity.Metal ion induced allosteric transition in the catalytic activity of an artificial phosphodiesterase.Investigation of macrocyclisation routes to 1,4,7-triazacyclononanes: efficient syntheses from 1,2-ditosylamides.Metal complexes promoting catalytic cleavage of nucleic acids-biochemical tools and therapeutics.Why DNA Is a More Effective Scaffold than RNA in Nucleic Acid-Based Asymmetric Catalysis-Supramolecular Control of Cooperative Effects.Straightforward approach to efficient oxidative DNA cleaving agents based on Cu(II) complexes of heterosubstituted cyclens.meso-Mono-[4-(1,4,7-triazacyclononanyl)]-tri(phenyl)]porphyrin and the respective zinc(ii)-complex: complete characterization and biomolecules binding abilities.Cu(II) and Mn(II) complexes containing macroacyclic ligand: synthesis, DNA binding, and cleavage studies.Synthesis, characterization, and DNA-binding and -cleavage properties of dinuclear Cu(II) --salophen/salen complexes.Double strand DNA cleavage with a binuclear iron complex.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Artificial metallonucleases.
@ast
Artificial metallonucleases.
@en
type
label
Artificial metallonucleases.
@ast
Artificial metallonucleases.
@en
prefLabel
Artificial metallonucleases.
@ast
Artificial metallonucleases.
@en
P356
P1476
Artificial metallonucleases
@en
P2093
Paolo Scrimin
Umberto Tonellato
P304
P356
10.1039/B418164F
P407
P577
2005-02-22T00:00:00Z