Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cells
about
The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation.Differential lymphocyte and antibody responses in deer mice infected with Sin Nombre hantavirus or Andes hantavirus.Molecular signatures of the evolving immune response in mice following a Bordetella pertussis infection.Association of multiple sclerosis susceptibility variants and early attack location in the CNSRegulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι.Histone deacetylase 6 inhibition impairs effector CD8 T-cell functions during skin inflammation.Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation.Dual Function of the IRF8 Transcription Factor in Autoimmune Uveitis: Loss of IRF8 in T Cells Exacerbates Uveitis, Whereas Irf8 Deletion in the Retina Confers ProtectionInterferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.Identification of CD3+CD4-CD8- T cells as potential regulatory cells in an experimental murine model of graft-versus-host skin disease (GVHD).Transcription factor IRF8 controls Th1-like regulatory T-cell functionImmune signatures of protective spleen memory CD8 T cellsBiallelic mutations in IRF8 impair human NK cell maturation and functionDendritic cell analysis in primary immunodeficiencyCurtailed T-cell activation curbs effector differentiation and generates CD8+ T cells with a naturally-occurring memory stem cell phenotype.IRF8-dependent molecular complexes control the Th9 transcriptional program.Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.Th17 cell differentiation proceeds independently of IRF8.
P2860
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P2860
Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@ast
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@en
type
label
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@ast
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@en
prefLabel
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@ast
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@en
P2093
P2860
P356
P1476
Interferon regulatory factor 8 ...... differentiation of CD8 T cells
@en
P2093
Atshushi Terunuma
Fumi Miyagawa
Hong Zhang
Keiko Ozato
Stephen I Katz
Yutaka Tagaya
P2860
P304
12123-12128
P356
10.1073/PNAS.1201453109
P407
P577
2012-07-10T00:00:00Z