A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies.
about
The amino terminus of herpes simplex virus 1 glycoprotein K is required for virion entry via the paired immunoglobulin-like type-2 receptor alphaA single intramuscular vaccination of mice with the HSV-1 VC2 virus with mutations in the glycoprotein K and the membrane protein UL20 confers full protection against lethal intravaginal challenge with virulent HSV-1 and HSV-2 strains.Mutations within the pathogenic region of herpes simplex virus 1 gK signal sequences alter cell surface expression and neurovirulenceChanges in Corneal Innervation after HSV-1 Latency Established with Different Reactivation Phenotypes.Herpes Simplex Vaccines: Prospects of Live-attenuated HSV Vaccines to Combat Genital and Ocular infections.Single dose of glycoprotein K (gK)-deleted HSV-1 live-attenuated virus protects mice against lethal vaginal challenge with HSV-1 and HSV-2 and induces lasting T cell memory immune responsesCell entry mechanisms of HSV: what we have learned in recent years.Deletion of a Predicted β-Sheet Domain within the Amino Terminus of Herpes Simplex Virus Glycoprotein K Conserved among Alphaherpesviruses Prevents Virus Entry into Neuronal Axons.Herpes simplex virus Membrane Fusion.Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons.Functional hierarchy of herpes simplex virus type-1 membrane proteins in corneal infection and virus transmission to ganglionic neurons.A replication competent HSV-1(McKrae) with a mutation in the amino-terminus of glycoprotein K (gK) is unable to infect mouse trigeminal ganglia after cornea infection.Inner tegument proteins of Herpes Simplex Virus are sufficient for intracellular capsid motility in neurons but not for axonal targeting.The Amino-terminus of HSV-1 Glycoprotein K (gK) is Required for gB Binding to Akt, Release of Intracellular Calcium and Fusion of the Viral Envelope with Plasma Membranes.
P2860
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P2860
A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@ast
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@en
type
label
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@ast
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@en
prefLabel
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@ast
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@en
P2093
P2860
P356
P1433
P1476
A herpes simplex virus 1 (McKr ...... ess from neuronal cell bodies.
@en
P2093
Ahmad Saied
Andrew T David
Anu Charles
Konstantin G Kousoulas
Ramesh Subramanian
Vladimir N Chouljenko
P2860
P304
P356
10.1128/MBIO.00144-12
P577
2012-07-24T00:00:00Z