Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors. - Wikidata - awgldk - TriplyDB

Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.

Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.

http://www.wikidata.org/entity/Q36146795

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Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy Microglia P2Y₆ receptors mediate nitric oxide release and astrocyte apoptosis Enhancement of glucose uptake in mouse skeletal muscle cells and adipocytes by P2Y6 receptor agonists Purinergic signaling induces thrombospondin-1 expression in astrocytes Permeation of fluorophore-conjugated phalloidin into live hair cells of the inner ear is modulated by P2Y receptors.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Development of selective agonists and antagonists of P2Y receptors.Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation.P2Y receptors and atherosclerosis in apolipoprotein E-deficient mice Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells.Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells.Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium.P2Y nucleotide receptors: promise of therapeutic applications Agonists and antagonists for P2 receptors.P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.P2Y6 receptor-mediated proinflammatory signaling in human bronchial epithelia.Molecular recognition at adenine nucleotide (P2) receptors in platelets.The impact of commercially available purinergic ligands on purinergic signalling research.Medicinal chemistry of adenosine, P2Y and P2X receptors.Pharmacological characterization of uracil nucleotide-preferring P2Y receptors modulating intestinal motility: a study on mouse ileum.Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor.UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis Thymidine 5'-O-monophosphorothioate induces HeLa cell migration by activation of the P2Y6 receptor.P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells.Regulation of neuronal ion channels via P2Y receptors.Extracellular nucleotides mediate LPS-induced neutrophil migration in vitro and in vivo.Microglia P2Y6 receptor is related to Parkinson's disease through neuroinflammatory process Novel vasocontractile role of the P2Y₁₄ receptor: characterization of its signalling in porcine isolated pancreatic arteries.P2X and P2Y nucleotide receptors as targets in cardiovascular disease.Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement.Altered purinergic receptor-Ca²⁺ signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells.Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3 Cardiomyocyte death induced by ischaemic/hypoxic stress is differentially affected by distinct purinergic P2 receptors.Apical versus basolateral P2Y(6) receptor-mediated Cl(-) secretion in immortalized bronchial epithelia.P2Y6 Receptor Antagonist MRS2578 Inhibits Neutrophil Activation and Aggregated Neutrophil Extracellular Trap Formation Induced by Gout-Associated Monosodium Urate Crystals.Development of a comprehensive set of P2 receptor pharmacological research compounds Modulation of neutrophil apoptosis by antimicrobial peptides.Activated microglia cause reversible apoptosis of pheochromocytoma cells, inducing their cell death by phagocytosis.Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo.

P2860

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P2860

Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.

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2004 nî lūn-bûn

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P2860

Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase

Tumor necrosis factor alpha-induced apoptosis in astrocytes is prevented by the activation of P2Y6, but not P2Y4 nucleotide receptors

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Receptors for purines and pyrimidines

Differential coupling of the human P2Y(11) receptor to phospholipase C and adenylyl cyclase

High affinity acylating antagonists for the A1 adenosine receptor: identification of binding subunit

Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety.

Expression of the P2Y6 purinergic receptor in human T cells infiltrating inflammatory bowel disease.

Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.

Characterisation of subtypes of the P2X and P2Y families of ATP receptors in the foetal human heart.

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