Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.
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Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosisPretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expressionNitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signalingPharmacokinetics of intravenous nitrosylcobalamin, an antitumor agent, in healthy Beagle dogs: a pilot study.A Stability-Indicating HPLC Method for the Determination of Nitrosylcobalamin (NO-Cbl), a Novel Vitamin B12 Analog.Immunohistochemical quantification of the vitamin B12 transport protein (TCII), cell surface receptor (TCII-R) and Ki-67 in human tumor xenografts.PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy.TNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.Cytotoxic and immune-sensitizing properties of nitric oxide-modified Saquinavir in iNOS-positive human melanoma cells.Trichothecin induces cell death in NF-κB constitutively activated human cancer cells via inhibition of IKKβ phosphorylation.Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma.Role of nuclear factor-kappa B in melanoma.Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.Honokiol is a potent scavenger of superoxide and peroxyl radicals.Homoharringtonine, a clinically approved anti-leukemia drug, sensitizes tumor cells for TRAIL-induced necroptosis.Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a novel Akt/NF-κB signalling inhibitor.Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanoma outgrowth in vitro and in vivo.Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation.TRAIL and vitamins: opting for keys to castle of cancer proteome instead of open sesame.Nitric oxide sensitizes prostate carcinoma cell lines to TRAIL-mediated apoptosis via inactivation of NF-kappa B and inhibition of Bcl-xl expression.Cisplatin-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts.Inactivation of nuclear factor κB by MIP-based drug combinations augments cell death of breast cancer cells.
P2860
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P2860
Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@ast
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@en
type
label
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@ast
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@en
prefLabel
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@ast
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@en
P2093
P2860
P356
P1476
Suppression of NF-kappa B surv ...... -tumor effects of Apo2L/TRAIL.
@en
P2093
Alex Almasan
Bei H Morrison
Daniel J Lindner
Ernest C Borden
Joseph A Bauer
Joseph A DiDonato
Joseph A Lupica
Rhonda K Oates
P2860
P304
39461-39469
P356
10.1074/JBC.M306111200
P407
P577
2003-07-24T00:00:00Z