Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques.
about
Animal Models for HIV Cure ResearchEx vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotypeImmunopathogenesis of simian immunodeficiency virus infection in nonhuman primatesRapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensed challenge window.Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replicationA novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques.Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.Modeling tuberculosis in nonhuman primates.Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.Broadening of Virus-Specific CD8+ T-Cell Responses Is Indicative of Residual Viral Replication in Aviremic SIV ControllersConditional Immune Escape during Chronic Simian Immunodeficiency Virus InfectionAcute Viral Escape Selectively Impairs Nef-Mediated Major Histocompatibility Complex Class I Downmodulation and Increases Susceptibility to Antiviral T CellsVaccination with Live Attenuated Simian Immunodeficiency Virus (SIV) Protects from Mucosal, but Not Necessarily Intravenous, Challenge with a Minimally Heterologous SIV.Adoptive transfer of lymphocytes isolated from simian immunodeficiency virus SIVmac239Δnef-vaccinated macaques does not affect acute-phase viral loads but may reduce chronic-phase viral loads in major histocompatibility complex-matched recipients.Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus.Haplessly hoping: macaque major histocompatibility complex made easy.Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point.T cell response specificity and magnitude against SIVmac239 are not concordant in major histocompatibility complex-matched animals.Mauritian cynomolgus macaques with M3M4 MHC genotype control SIVmac251 infection.The Importance of Understanding MHC-I Diversity in Nonhuman Primate Models of Human Infectious Diseases.Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.Maintenance of AP-2 Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses.Whole genome sequencing in the search for genes associated with the control of SIV infection in the Mauritian macaque model.
P2860
Q26767476-50B60959-374E-412E-A700-F40B4F04B1BAQ27322650-1052F6BF-D15B-4724-9C12-850B80EEC59AQ33355730-91D66DE4-C2A2-4074-8376-5244E47C08B6Q34108798-741700A6-0A33-4936-8D71-E4A9F7AF7E67Q34466825-79E3EBF3-5EC2-407E-ABE3-E1F9219FB644Q34559322-A3C06326-F7D0-44DF-90A1-560AFCEE6F43Q34613552-4EE9D034-B782-4E78-844F-C6F2822DFC57Q34930509-505B0FFB-D6ED-4098-A2BD-FD47F7A5989BQ34984237-7F6FB3CA-C8D4-4780-8673-33F570EAF8E3Q35831895-83B7D95E-2F69-4871-8489-CCF9E1AFF2C9Q36433848-DF83073F-4BB6-4A85-8A17-CF7D5B9C39DBQ36523922-45073120-E2D5-42FB-ABD7-191438DC0CBBQ36950929-86B05875-6C0C-478A-8C8C-1C980F9CF4ABQ36978921-A7930AED-B099-432B-AFC6-EDAFB4CFEB10Q37123354-EA509E60-16CD-4312-9448-6574F2879685Q37271239-A71C1F4F-994C-4122-8984-2BF142A817EEQ37547306-FF6A1572-B292-4764-A3C5-DF7F909DD963Q39326760-97BA38B3-0E3F-415A-A06E-64A052E79E8FQ40106524-96122072-963F-4B23-853B-3F50DC4C59B8Q40510062-31DE9ED1-79E0-4B1D-B4CC-51DB4DD1439EQ45768173-29654A7B-6084-470F-A107-07F226740DFDQ47296340-3E20983B-5EC7-40AB-B21D-F4312AE4C2CBQ54217740-151908C5-D25E-4B48-A090-9EDEB4B1321F
P2860
Specific CD8+ T cell responses correlate with control of simian immunodeficiency virus replication in Mauritian cynomolgus macaques.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@ast
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@en
type
label
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@ast
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@en
prefLabel
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@ast
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@en
P2093
P2860
P50
P356
P1433
P1476
Specific CD8+ T cell responses ...... Mauritian cynomolgus macaques.
@en
P2093
Brian T Cain
Emily N Chin
Emma Gostick
Ericka A Becker
Jeffrey D Lifson
Justin M Greene
Matthew Scarlotta
Max Harris
Melisa L Budde
Michael Piatak
P2860
P304
P356
10.1128/JVI.00716-12
P407
P577
2012-05-09T00:00:00Z