Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
about
Tumor-specific Th17-polarized cells eradicate large established melanomaTranslational utility of experimental autoimmune encephalomyelitis: recent developmentsDesign of oral agents for the management of multiple sclerosis: benefit and risk assessment for dimethyl fumarateIL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelinationThe IL-17 pathway as a major therapeutic target in autoimmune diseasesOpposing roles of STAT4 and Dnmt3a in Th1 gene regulationTherapeutic modulators of STAT signalling for human diseasesT-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17.Th17 cells: effector T cells with inflammatory properties.Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis.Involvement of the janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis.Th1 and Th17 cells: adversaries and collaboratorsLeptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis.Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexusDecreased signal transducers and activators of transcription (STAT) protein expression in lymphatic organs during EAE development in mice.LXR-mediated inhibition of CD4+ T helper cells.Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitisAnti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitisLive-cell imaging of the association of STAT6-GFP with mitochondriaStat4 is critical for the balance between Th17 cells and regulatory T cells in colitisA genomic view of helper T cell subsets.Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation.STAT6 expression in multiple cell types mediates the cooperative development of allergic airway diseaseInterferon-β suppresses murine Th1 cell function in the absence of antigen-presenting cells.Signatures of human regulatory T cells: an encounter with old friends and new playersElevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegenerationSTAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE.Regulatory functions of CD8+CD28- T cells in an autoimmune disease modelAltered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease.Janus-like effects of type I interferon in autoimmune diseases.MOG(35-55) i.v suppresses experimental autoimmune encephalomyelitis partially through modulation of Th17 and JAK/STAT pathways.Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.The role of IL-2 in the activation and expansion of regulatory T-cells and the development of experimental autoimmune encephalomyelitisSystems-based medicine approaches to understand and treat complex diseases. The example of multiple sclerosis.Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines.A rush to judgment on Th17Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis.Maintaining immunological tolerance with Foxp3.Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis.
P2860
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P2860
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@ast
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@en
type
label
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@ast
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@en
prefLabel
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@ast
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@en
P2093
P2860
P356
P1476
Effect of targeted disruption ...... l autoimmune encephalomyelitis
@en
P2093
A D Salama
M H Sayegh
M J Grusby
N Najafian
S J Khoury
P2860
P304
P356
10.1172/JCI200112563
P407
P577
2001-09-01T00:00:00Z