EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression. - Wikidata - awgldk - TriplyDB

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

http://www.wikidata.org/entity/Q36169265

about

Customizing the genome as therapy for the β-hemoglobinopathies Histone lysine methyltransferases as anti-cancer targets for drug discovery Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2 Chemical probes targeting epigenetic proteins: Applications beyond oncology.New insights into sickle cell disease: mechanisms and investigational therapies.Alterations in nuclear structure promote lupus autoimmunity in a mouse model.Epigenetic Medicinal Chemistry.CRISPR-Cas9 technology and its application in haematological disorders.Clinically-oriented proteomic investigation of sickle cell disease: Opportunities and challenges.Use of genome-editing tools to treat sickle cell disease.Hemoglobin genetics: recent contributions of GWAS and gene editing.Gene Therapy for β-Hemoglobinopathies.The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration.Fetal haemoglobin induction in sickle cell disease.Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies.Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells Fetal Hemoglobin Induction by Epigenetic Drugs

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P2860

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

http://www.wikidata.org/entity/Q36169265

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression

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Aline Renneville

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Benjamin L Ebert

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Bradley E Bernstein

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P2860

Genome engineering using the CRISPR-Cas9 system

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Combinatorial patterns of histone acetylations and methylations in the human genome

High-resolution profiling of histone methylations in the human genome

Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

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