The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice. - Wikidata - awgldk - TriplyDB

The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice.

The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice.

http://www.wikidata.org/entity/Q36173756

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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes Purinergic signalling and diabetes Paracrine and autocrine interactions in the human islet: more than meets the eye Purinergic signalling in endocrine organs Vesicular nucleotide transporter-mediated ATP release regulates insulin secretion.ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell Impairment of vesicular ATP release affects glucose metabolism and increases insulin sensitivity.Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans.Pharmacological interventions that directly stimulate or modulate insulin secretion from pancreatic beta-cell: implications for the treatment of type 2 diabetes.Extracellular ATP and other nucleotides-ubiquitous triggers of intercellular messenger release.Evidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and insulin secretion in mouse pancreatic islets.Purinergic receptors in the endocrine and exocrine pancreas.New insights into the architecture of the islet of Langerhans: a focused cross-species assessment.The Different Faces of the Pancreatic Islet.Identification of a promising drug candidate for the treatment of type 2 diabetes based on a P2Y(1) receptor agonist.The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance.Identification of the ectonucleotidases expressed in mouse, rat, and human Langerhans islets: potential role of NTPDase3 in insulin secretion.A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold.Autocrine activation of P2Y1 receptors couples Ca (2+) influx to Ca (2+) release in human pancreatic beta cells.P2Y1 transient overexpression induced mineralization in spinal ligament cells derived from patients with ossification of the posterior longitudinal ligament of the cervical spine.

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P2860

The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice.

http://www.wikidata.org/entity/Q36173756

description

2005 nî lūn-bûn

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Catherine Léon

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P2860

Identification of the platelet ADP receptor targeted by antithrombotic drugs

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study

Method for the isolation of intact islets of Langerhans from the rat pancreas

Receptors for purines and pyrimidines

Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells

Regulation of rat hepatocyte function by P2Y receptors: focus on control of glycogen phosphorylase and cyclic AMP by 2-methylthioadenosine 5'-diphosphate

Cellular mechanisms of insulin resistance

P2 receptor agonists stimulate insulin release from human pancreatic islets.

Key role of the P2Y(1) receptor in tissue factor-induced thrombin-dependent acute thromboembolism: studies in P2Y(1)-knockout mice and mice treated with a P2Y(1) antagonist.

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