Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys.

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Stem cells and stem cell-derived tissues and their use in safety assessment.Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.Bioengineered Cardiac Tissue Based on Human Stem Cells for Clinical Application.

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P2860

Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys.

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http://www.wikidata.org/entity/Q36176544

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Investigation of mechanism of ...... pointes in cynomolgus monkeys.

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Investigation of mechanism of ...... pointes in cynomolgus monkeys.

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Investigation of mechanism of ...... pointes in cynomolgus monkeys.

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Investigation of mechanism of ...... pointes in cynomolgus monkeys.

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Investigation of mechanism of ...... pointes in cynomolgus monkeys.

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Investigation of mechanism of ...... pointes in cynomolgus monkeys.

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P2093

C Frantz

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D L Misner

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J Ly

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K L Kolaja

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L Guo

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M Albassam

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M R Gralinski

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P B Senese

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Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects

Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity.

Overcoming HERG affinity in the discovery of the CCR5 antagonist maraviroc.

Overcoming hERG affinity in the discovery of maraviroc; a CCR5 antagonist for the treatment of HIV.

In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: application to the preclinical cardiovascular safety pharmacology of a new chemical entity.

Cellular basis of drug-induced torsades de pointes

Spiropiperidine CCR5 antagonists.

Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulation

A search to predict potential for drug-induced cardiovascular toxicity.

Antidepressants: their effects on cardiac channels, QT prolongation and Torsade de Pointes.

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2771-2786

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scholarly article

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10.1111/J.1476-5381.2011.01756.X

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English

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165

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Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys.

about

P2860

P2860

Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys.

description

name

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P1433

P1476

P2093

P2860

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P5875

P698

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P1433

P1476

P2093

P2860

P304

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P356

P407

P433

P478

P577

P5875

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P932