The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.
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Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATcNFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymusPhysical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cellsActivation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand bindingGM-CSF promoter chromatin remodelling and gene transcription display distinct signal and transcription factor requirementsA reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomesEpigenetic regulation of inducible gene expression in the immune systemATP-dependent chromatin remodeling in T cellsReceptor Signaling Directs Global Recruitment of Pre-existing Transcription Factors to Inducible ElementsHigh-resolution mapping and characterization of open chromatin across the genomeRole of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytesRunx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancerNFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificityPhosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cellsFamilial eosinophilia maps to the cytokine gene cluster on human chromosomal region 5q31-q33.Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in GambiansDoxorubicin-mediated apoptosis in glioma cells requires NFAT3.Histone dynamics on the interleukin-2 gene in response to T-cell activation.Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cellsRequirement for transcription factor NFAT in interleukin-2 expressionNovel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locusErythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells.Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis.Calcineurin and hypertrophic heart disease: novel insights and remaining questions.Identification of a DNA binding site for the nuclear factor YY1 in the human GM-CSF core promoter.Costimulation of cytokine gene expression in T cells by the human T leukemia/lymphotropic virus type 1 trans activator Tax.A sequence-specific single-strand DNA binding protein that contacts repressor sequences in the human GM-CSF promoterChanges in chromatin accessibility across the GM-CSF promoter upon T cell activation are dependent on nuclear factor kappaB proteins.The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesisHuman granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/cDeterminants of a transcriptionally competent environment at the GM-CSF promoter.The human granulocyte-macrophage colony-stimulating factor gene is autonomously regulated in vivo by an inducible tissue-specific enhancer.Ca2+-operated transcriptional networks: molecular mechanisms and in vivo models.Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cellsFc epsilon RI-mediated induction of nuclear factor of activated T-cells.A two-hit mechanism for vitamin D3-mediated transcriptional repression of the granulocyte-macrophage colony-stimulating factor gene: vitamin D receptor competes for DNA binding with NFAT1 and stabilizes c-Jun.Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3.DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells.Apremilast: a PDE4 inhibitor for the treatment of psoriatic arthritis.
P2860
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P2860
The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The granulocyte-macrophage col ...... losporin A-sensitive enhancer.
@ast
The granulocyte-macrophage col ...... losporin A-sensitive enhancer.
@en
type
label
The granulocyte-macrophage col ...... losporin A-sensitive enhancer.
@ast
The granulocyte-macrophage col ...... losporin A-sensitive enhancer.
@en
prefLabel
The granulocyte-macrophage col ...... losporin A-sensitive enhancer.
@ast
The granulocyte-macrophage col ...... losporin A-sensitive enhancer.
@en
P2093
P2860
P356
P1476
The granulocyte-macrophage col ...... closporin A-sensitive enhancer
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.6.2466
P407
P577
1993-03-01T00:00:00Z