Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.
about
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.Genome engineering of stem cell organoids for disease modeling.Insights from Global Analyses of Long Noncoding RNAs in Breast CancerMolecular and phenotypic biomarkers of agingGuideScan software for improved single and paired CRISPR guide RNA designFunctional interrogation of non-coding DNA through CRISPR genome editing.The Many Faces of Long Noncoding RNAs in Cancer.Long noncoding RNA: a crosslink in biological regulatory network.Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease.State of the art technologies to explore long non-coding RNAs in cancer.The emerging molecular biology toolbox for the study of long noncoding RNA biology.CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments.lncRNAs in development and disease: from functions to mechanisms.A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells.Elucidating the Role of Host Long Non-Coding RNA during Viral Infection: Challenges and Paths Forward.Human gene essentiality.CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.Forging our understanding of lncRNAs in the brain.Simple Meets Single: The Application of CRISPR/Cas9 in Haploid Embryonic Stem Cells.Mechanisms of Long Non-Coding RNAs in the Assembly and Plasticity of Neural Circuitry.From biomarkers to therapeutic targets-the promises and perils of long non-coding RNAs in cancer.CRISPR/Cas9 library screening for drug target discovery.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.CRISPR/Cas9-Mediated Genome Editing in Epstein-Barr Virus-Transformed Lymphoblastoid B-Cell LinesHigh-Throughput Approaches to Pinpoint Function within the Noncoding Genome.PICKLES: the database of pooled in-vitro CRISPR knockout library essentiality screens.Enhanced Genome Editing Tools For Multi-Gene Deletion Knock-Out Approaches Using Paired CRISPR sgRNAs in CHO Cells.PANDAR: a pivotal cancer-related long non-coding RNA in human cancers.Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.LncRNA-ATB: An indispensable cancer-related long noncoding RNA.Long non-coding RNA tagging and expression manipulation via CRISPR/Cas9-mediated targeted insertion.Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.LncRNA HOTAIR promotes cell migration and invasion by regulating MKL1 via inhibition miR206 expression in HeLa cells.CRISPR/Cas9-mediated noncoding RNA editing in human cancers.When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells.Functional Classification and Experimental Dissection of Long Noncoding RNAs.Cas9-mediated excision of proximal DNaseI/H3K4me3 signatures confers robust silencing of microRNA and long non-coding RNA genes.Therapeutic Targeting of Long Non-Coding RNAs in Cancer.Noncoding RNAs in the Regulation of Pluripotency and Reprogramming.The role of long noncoding RNAs in cancer: the dark matter matters.
P2860
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P2860
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@ast
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@en
type
label
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@ast
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@en
prefLabel
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@ast
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@en
P2093
P2860
P50
P356
P1433
P1476
Genome-scale deletion screenin ...... guide RNA CRISPR-Cas9 library.
@en
P2093
Chen-Hao Chen
Jingyu Peng
Jingze Liu
Myles Brown
Pengfei Yuan
Shiyou Zhu
Tengfei Xiao
P2860
P2888
P304
P356
10.1038/NBT.3715
P577
2016-10-31T00:00:00Z