Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma
about
Current and developing synthetic pharmacotherapy for treating relapsed/refractory multiple myeloma.Epigenetic regulatory mutations and epigenetic therapy for multiple myeloma.HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells.The proteasome and proteasome inhibitors in multiple myeloma.Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma.Histone deacetylase inhibitors downregulate CCR4 expression and decrease mogamulizumab efficacy in CCR4-positive mature T-cell lymphomas.Suppression of FGFR3- and MYC-dependent oncogenesis by tubacin: association with HDAC6-dependent and independent activities.A Brief Overview of Two Major Strategies in Diversity-Oriented Synthesis: Build/Couple/Pair and Ring-DistortionThe biological significance of histone modifiers in multiple myeloma: clinical applicationsThe Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative DiseaseSilencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia
P2860
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P2860
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Discovery of selective small-m ...... resistance in multiple myeloma
@ast
Discovery of selective small-m ...... resistance in multiple myeloma
@en
type
label
Discovery of selective small-m ...... resistance in multiple myeloma
@ast
Discovery of selective small-m ...... resistance in multiple myeloma
@en
prefLabel
Discovery of selective small-m ...... resistance in multiple myeloma
@ast
Discovery of selective small-m ...... resistance in multiple myeloma
@en
P2093
P2860
P50
P356
P1476
Discovery of selective small-m ...... resistance in multiple myeloma
@en
P2093
Edward Greenberg
Francesca Cottini
Guillermina Estiu
Güllü Görgün
Hiroto Ohguchi
James E Bradner
Jennifer A Perry
Meaghan E Colling
Naoya Mimura
P2860
P304
13162-13167
P356
10.1073/PNAS.1608067113
P407
P577
2016-10-31T00:00:00Z