Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
about
Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevanceEmerging concepts of epigenetic dysregulation in hematological malignanciesEpigenetics in Cancer: A Hematological PerspectiveData on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Hematopoiesis "awakens": Evolving technologies, the force behind them.The three-dimensional cancer genome.HDAC8 Inhibition Blocks SMC3 Deacetylation and Delays Cell Cycle Progression without Affecting Cohesin-dependent Transcription in MCF7 Cancer Cells.The role of mutations in the cohesin complex in acute myeloid leukemia.Cohesin mutations in human cancerASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis.Cohesin Mutations in Myeloid Malignancies.The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9.Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.Cohesin complex is a major player on the stage of leukemogenesis.Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.The Cohesin Complex Is Necessary for Epidermal Progenitor Cell Function through Maintenance of Self-Renewal Genes.Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia.Cohesin mutations: contributors to myeloid malignancies.Down-syndrome-like acute megakaryoblastic leukemia in a patient with Cornelia de Lange syndrome.HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity.Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia.Rings and Bricks: Expression of Cohesin Components is Dynamic during Development and Adult Life.Copy number profiling of adult relapsed B-cell precursor acute lymphoblastic leukemia reveals potential leukemia progression mechanisms.Prognostic impacts and dynamic changes of cohesin complex gene mutations in de novo acute myeloid leukemia.Enhancer dysfunction in leukemia.Association of mutations with morphologic dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities.Revealing nascent proteomics in signaling pathways and cell differentiation.Integrated analysis identified an intestinal-like and a diffuse-like gene sets that predict gastric cancer outcome.Expression of RAD21 immunoreactivity in myenteric neurons of the human and mouse small intestineDistinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization
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P2860
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@ast
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@en
type
label
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@ast
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@en
prefLabel
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@ast
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@en
P2093
P2860
P50
P356
P1476
Cohesin loss alters adult hema ...... o myeloproliferative neoplasms
@en
P2093
Beatriz Aranda-Orgilles
Clarisse Kayembe
Daniela Hoehn
Iannis Aifantis
Jasper Mullenders
Luisa Cimmino
Matthew Keller
Prem K Premsrirut
Priscillia Lhoumaud
P2860
P304
P356
10.1084/JEM.20151323
P407
P577
2015-10-05T00:00:00Z