Enhancing the promiscuous phosphotriesterase activity of a thermostable lactonase (GkaP) for the efficient degradation of organophosphate pesticides
about
Integrated (Meta) Genomic and Synthetic Biology Approaches to Develop New BiocatalystsMolecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase TemplateSwitching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263TrpCrystallization and preliminary X-ray diffraction analysis of the lactonaseVmoLac fromVulcanisaeta moutnovskiaActive site loop conformation regulates promiscuous activity in a lactonase from Geobacillus kaustophilus HTA426SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase.Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes.An efficient thermostable organophosphate hydrolase and its application in pesticide decontamination.Combinatorial evolution of phosphotriesterase toward a robust malathion degrader by hierarchical iteration mutagenesis.Binding modes of phosphotriesterase-like lactonase complexed with δ-nonanoic lactone and paraoxon using molecular dynamics simulations.Rational design of paraoxonase 1 (PON1) for the efficient hydrolysis of organophosphates.
P2860
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P2860
Enhancing the promiscuous phosphotriesterase activity of a thermostable lactonase (GkaP) for the efficient degradation of organophosphate pesticides
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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name
Enhancing the promiscuous phos ...... of organophosphate pesticides
@ast
Enhancing the promiscuous phos ...... of organophosphate pesticides
@en
type
label
Enhancing the promiscuous phos ...... of organophosphate pesticides
@ast
Enhancing the promiscuous phos ...... of organophosphate pesticides
@en
prefLabel
Enhancing the promiscuous phos ...... of organophosphate pesticides
@ast
Enhancing the promiscuous phos ...... of organophosphate pesticides
@en
P2093
P2860
P356
P1476
Enhancing the promiscuous phos ...... of organophosphate pesticides
@en
P2093
Guangyu Yang
Hai-Feng Chen
Zhi-Gang Qian
P2860
P304
P356
10.1128/AEM.01122-12
P407
P577
2012-07-13T00:00:00Z