mTOR coordinates protein synthesis, mitochondrial activity and proliferation. - Wikidata - awgldk - TriplyDB

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

http://www.wikidata.org/entity/Q36189549

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Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function Growth control mechanisms in neuronal regeneration Akt/mTOR mediated induction of bystander effect signaling in a nucleus independent manner in irradiated human lung adenocarcinoma epithelial cells.Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1.Stabilization of 4E-BP1 by PI3K kinase and its involvement in CHK2 phosphorylation in the cellular response to radiation.rpS6 regulates blood-testis barrier dynamics through Arp3-mediated actin microfilament organization in rat sertoli cells. An in vitro study nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs An evolutionary perspective of AMPK-TOR signaling in the three domains of life.GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells.Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease Inhibition of mTOR signaling protects photoreceptor cells against serum deprivation by reducing oxidative stress and inducing G2/M cell cycle arrest Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome.RES-529: a PI3K/AKT/mTOR pathway inhibitor that dissociates the mTORC1 and mTORC2 complexes.Chronic rapamycin treatment on the nutrient utilization and metabolism of juvenile turbot (Psetta maxima).Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma.Hypoxia and classical activation limits Mycobacterium tuberculosis survival by Akt-dependent glycolytic shift in macrophages.Ion mobility-enhanced MS(E)-based label-free analysis reveals effects of low-dose radiation post contextual fear conditioning training on the mouse hippocampal proteome.Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity.Altered Mitochondrial Signalling and Metabolism in Cancer.An overview of experimental and early investigational therapies for the treatment of polycystic kidney disease.Dual abrogation of MNK and mTOR: a novel therapeutic approach for the treatment of aggressive cancers.Concentration-dependent metabolic effects of metformin in healthy and Fanconi anemia lymphoblast cells.The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth A researcher's guide to the galaxy of IRESs.The Role of Exercise and TFAM in Preventing Skeletal Muscle Atrophy.Non-coding RNAs: the dark side of nuclear-mitochondrial communication.Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria.Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy.Mitochondrial dynamics and cancer.MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells.Divergent Metabolic Regulation of Autophagy and mTORC1-Early Events in Alzheimer's Disease?Follistatin Gene Therapy for Sporadic Inclusion Body Myositis Improves Functional Outcomes.Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.IER3IP1 deficiency leads to increased β-cell death and decreased β-cell proliferation.Cancer: Linking Powerhouses to Suicidal Bags.Effects of rapamycin on cerebral oxygen supply and consumption during reperfusion after cerebral ischemia.Inhibition of mTOR reduces lipotoxic cell death in primary macrophages through an autophagy-independent mechanism

P2860

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P2860

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

http://www.wikidata.org/entity/Q36189549

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

@zh-cn

name

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

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mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

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type

label

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

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mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

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mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

@ast

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

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15384101.2014.991572

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P1476

mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

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P2093

Julie St-Pierre

http://www.w3.org/2001/XMLSchema#string

Masahiro Morita

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Michael Pollak

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Creative Commons Attribution-NonCommercial 3.0 Unported

P2860

Hallmarks of Cancer: The Next Generation

Activation of mTORC2 by association with the ribosome

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

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473-480

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10.4161/15384101.2014.991572

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4

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14

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Ivan Topisirovic

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2015-01-01T00:00:00Z

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270908722

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25590164

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biomedical investigative technique

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4615141

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