IGFBP2 potentiates nuclear EGFR-STAT3 signaling. - Wikidata - awgldk - TriplyDB

IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

http://www.wikidata.org/entity/Q36189855

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Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies.Recent Insights into Insulin-Like Growth Factor Binding Protein 2 Transcriptional Regulation.Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution.Role of STAT3 in Genesis and Progression of Human Malignant Gliomas.Epidermal growth factor receptor activity is elevated in glioma cancer stem cells and is required to maintain chemotherapy and radiation resistance.IGFBP2 Activates the NF-κB Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma.TRIM59 promotes gliomagenesis by inhibiting TC45 dephosphorylation of STAT3.The MDA-9/Syntenin/IGF-1R/STAT3 axis directs prostate cancer invasion.Insulin-Like Growth Factor-Binding Proteins of Teleost Fishes.Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

http://www.wikidata.org/entity/Q36189855

description

2015 nî lūn-bûn

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name

IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

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IGFBP2 potentiates nuclear EGFR-STAT3 signaling

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C Y Chua

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D E Cogdell

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H Haapasalo

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K J Granberg

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L M Moore

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M J Annala

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M Verploegen

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W K Cavenee

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P2860

PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its growth-promoting actions

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Nuclear activities of basic fibroblast growth factor: potentiation of low-serum growth mediated by natural or chimeric nuclear localization signals

Spatial and temporal organization of signaling pathways

EGF receptor trafficking: consequences for signaling and cancer

Epidermal growth factor-related peptides and their receptors in human malignancies

IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients

ADAMs: key components in EGFR signalling and development

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

Endocytosis and signalling: intertwining molecular networks

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738-747

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10.1038/ONC.2015.131

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