Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases.
about
Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimagingBrain endothelial cell-cell junctions: how to "open" the blood brain barrierBypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia TherapyMolecular determinants of blood-brain barrier permeationCyclooxygenase-2 in epilepsy.Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL MiceThe molecular constituents of the blood-brain barrierTissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in ratProfiles of multidrug resistance protein-1 in the peripheral blood mononuclear cells of patients with refractory epilepsyEffects of sertraline and fluoxetine on p-glycoprotein at barrier sites: in vivo and in vitro approachesA novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drugPharmacokinetics and Metabolism of 4R-CembranoidModeling the Slow CD4+ T Cell Decline in HIV-Infected IndividualsFocused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncologySusceptibility of juvenile and adult blood-brain barrier to endothelin-1: regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus.Nanomedicine in the diagnosis and therapy of neurodegenerative disorders.Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled ratsViral nanoparticles associate with regions of inflammation and blood brain barrier disruption during CNS infectionCentral neurotoxicity in cancer chemotherapy: pharmacogenetic insights.N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrierPositron emission tomography molecular imaging for drug development.Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active effluxPgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat dataCelecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy.Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport.Polymorphism of ABCB1/MDR1 C3435T in children and adolescents with partial epilepsy is due to different criteria for drug resistance - preliminary results.The blood-brain barrier in health and disease.In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish.Reliable disease biomarkers characterizing and identifying electrohypersensitivity and multiple chemical sensitivity as two etiopathogenic aspects of a unique pathological disorder.Effect of transporter inhibition on the distribution of cefadroxil in rat brainLysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PETCerebral uptake of drugs in humans.Roles of P-glycoprotein and multidrug resistance protein in transporting para-aminosalicylic acid and its N-acetylated metabolite in mice brain.Homeostatic bioenergetic network regulation - a novel concept to avoid pharmacoresistance in epilepsy.PharmGKB summary: methotrexate pathway.Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity.Brain regional pharmacokinetics of p-aminosalicylic acid and its N-acetylated metabolite: effectiveness in chelating brain manganeseIdentification of trichlormethiazide as a Mdr1a/b gene expression enhancer via a dual secretion-based promoter assay.Endogenous repair signaling after brain injury and complementary bioengineering approaches to enhance neural regeneration
P2860
Q21223671-C5DF2FC6-0275-43F5-BBB1-34AF01CE9D90Q24654117-3FD4A20E-C741-47FD-98FD-BF37D9E46816Q26780502-5918818A-750D-469E-B7E9-68122EA63FCFQ26797482-B2216A35-D4E0-48D6-856D-7D997164D952Q26827095-581E28D9-564D-4D36-A744-5D116EB7CBC9Q27324510-97A14C85-7195-48B8-861B-473CB931D600Q28087222-0F9A841D-A31E-4DE7-9AD9-5CAA6E9BD0B8Q28387762-8960229C-6A75-4B8A-BE8C-ABBB11F34EB0Q28483667-984492F9-1C89-4EF6-B885-9F3605A44EA1Q28487360-96B98C67-1D95-46C4-8724-6532978CE348Q28540639-5CBB68FD-79EC-453B-84A3-F6F5632F4EB3Q28545024-CE973D87-9A16-4178-9CD0-0F26A1941E35Q28551803-A171C543-471A-43F8-BFF8-AD0D2C7D6C24Q30434475-7F97E271-DEFE-4B56-8A55-8872907F700CQ30532529-646E03B8-F88C-43C7-AFF8-2FC0AB4E653AQ30993837-54C9F83D-889B-4183-90E7-F2EB46FD22D6Q33726019-7CDD4C26-C8A4-4D59-A29A-A122218EA9D8Q33772891-FF57303A-1841-4292-BE84-88C60CB3427FQ33804179-AEF9EA1F-466B-4905-B710-AA7CAF2D0A7DQ33857581-294861D3-D757-4944-AC9C-C776B4626C71Q33891067-B9976385-1072-4A5C-AE7C-426F612D273FQ33991881-8279E263-0E5A-48AB-BD84-01C9E4257D70Q34028148-ED2E29B0-6288-4E2A-8C5A-166D491BB4CFQ34100185-16D7B8D2-F273-4438-BBF9-8A9142FC0580Q34112939-1702C8CF-6517-4A27-91BB-C1116FE8A567Q34124847-CA1ADAEF-154C-4A55-99A9-F06AC6975C86Q34237989-970DC6C1-3719-457A-BFBB-D6D069496285Q34320420-816414D7-6DD7-4AC1-9525-C7F1DBDE9C35Q34380482-0DC7924E-CEA5-4866-BFA0-865D794243DAQ34503321-A5499AE3-443D-4913-89C4-9E31C7E22401Q34544043-E374B530-63B7-4CAA-9A8D-0014D0BF36BEQ34572780-2BD0E764-4206-42BE-ABC7-1B6963E8DAA8Q34643571-C362A38E-ED82-4235-9DBB-6C9607401139Q34664482-2EE3C32B-E471-49B5-A25C-BB8026D76F4EQ35072901-1DFF01B0-276B-488C-905C-DE4CAB46ADCCQ35115680-FB2AD63B-B2B6-45D6-858D-C311787CF15CQ35212135-A73704B6-2DCC-4962-9D20-18319E74E1D0Q35264839-9EAC6F69-BE4D-4EC9-9BD1-31E51CBDA3F1Q35563239-1D175A9C-B480-4AE7-8FD8-15DC2843ED83Q35600150-7C4C7F07-5068-40D2-BCB7-EC565FB6F1C9
P2860
Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Role of drug efflux transporte ...... d treatment of brain diseases.
@ast
Role of drug efflux transporte ...... d treatment of brain diseases.
@en
type
label
Role of drug efflux transporte ...... d treatment of brain diseases.
@ast
Role of drug efflux transporte ...... d treatment of brain diseases.
@en
prefLabel
Role of drug efflux transporte ...... d treatment of brain diseases.
@ast
Role of drug efflux transporte ...... d treatment of brain diseases.
@en
P1476
Role of drug efflux transporte ...... d treatment of brain diseases.
@en
P2093
Heidrun Potschka
Wolfgang Löscher
P356
10.1016/J.PNEUROBIO.2005.04.006
P577
2005-05-01T00:00:00Z