JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors. - Wikidata - awgldk - TriplyDB

JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors.

JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors.

http://www.wikidata.org/entity/Q36199628

about

Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability.Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis Histone demethylase JMJD1C regulates esophageal cancer proliferation Via YAP1 signaling.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.Lysine-specific histone demethylases in normal and malignant hematopoiesis.Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development.JMJD1C Ensures Mouse Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming through Controlling MicroRNA Expression.Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c Plant homeodomain finger protein 2 as a novel IKAROS target in acute lymphoblastic leukemia.MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia.RUNX1-ETO Leukemia.Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.

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JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors.

http://www.wikidata.org/entity/Q36199628

description

2015 nî lūn-bûn

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2015年の論文

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JMJD1C is required for the sur ...... for key transcription factors.

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Genes & Development

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JMJD1C is required for the sur ...... for key transcription factors.

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Benoit Laurent

http://www.w3.org/2001/XMLSchema#string

Mo Chen

http://www.w3.org/2001/XMLSchema#string

Nan Zhu

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Robert G Roeder

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Rowena Eng

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Scott A Armstrong

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Xiaochuan Liu

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Yang Shi

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Zhanyun Tang

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Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ

A novel variant of the putative demethylase gene, s-JMJD1C, is a coactivator of the AR

Selective inhibition of BET bromodomains

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

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2123-2139

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10.1101/GAD.267278.115

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20

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29

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