RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis. - Wikidata - awgldk - TriplyDB

RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

http://www.wikidata.org/entity/Q36206674

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Concise review: programming human pluripotent stem cells into blood Stem Cell Modeling of Core Binding Factor Acute Myeloid Leukemia Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance Interplay between Transcription Factors and the Epigenome: Insight from the Role of RUNX1 in Leukemia Aberrant nuclear factor-kappa B activity in acute myeloid leukemia: from molecular pathogenesis to therapeutic target Zebrafish as a model for leukemia and other hematopoietic disorders Deficiency of the NR4A orphan nuclear receptor NOR1 in hematopoietic stem cells accelerates atherosclerosis A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia Discovering and understanding oncogenic gene fusions through data intensive computational approaches Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression Runx2-I isoform contributes to fetal bone formation even in the absence of specific N-terminal amino acids.Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.Enhancer alterations in cancer: a source for a cell identity crisis.Cis-regulatory elements are harbored in Intron5 of the RUNX1 gene.Identification of a DNA methylation signature in blood cells from persons with Down Syndrome.Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation.Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO.HNF1 regulates critical processes in the human epididymis epithelium RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia.Sex-specific effects of early life cadmium exposure on DNA methylation and implications for birth weight.Restoration of MYC-repressed targets mediates the negative effects of GM-CSF on RUNX1-ETO leukemogenicity.Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.The RUNX family in breast cancer: relationships with estrogen signaling.RUNX family: Regulation and diversification of roles through interacting proteins.Use of zebrafish embryos for small molecule screening related to cancer.RUNX1: A microRNA hub in normal and malignant hematopoiesis.Pontin is a critical regulator for AML1-ETO-induced leukemia.The RUNX1-PU.1 axis in the control of hematopoiesis.Aberrant AML1 gene expression in the diagnosis of childhood leukemias not characterized by AML1-involved cytogenetic abnormalities.Fusion genes in malignant neoplastic disorders of haematopoietic system.Runx1 Structure and Function in Blood Cell Development.miR-17 deregulates a core RUNX1-miRNA mechanism of CBF acute myeloid leukemia.An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies.Promoter hypermethylation-mediated down-regulation of RUNX3 gene in human brain tumors.RUNX1 cooperates with FLT3-ITD to induce leukemia.Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

http://www.wikidata.org/entity/Q36206674

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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Frontiers in Bioscience

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RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.

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Dong-Er Zhang

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Kentson Lam

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P2860

Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

Identification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue.

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

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10.2741/3977

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17

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