Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies.
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Both Epistasis and Diversifying Selection Drive the Structural Evolution of the Ebola Virus Glycoprotein Mucin-Like DomainA review of Phase I trials of Ebola virus vaccines: what can we learn from the race to develop novel vaccines?The ongoing evolution of antibody-based treatments for Ebola virus infection.Monoclonal antibodies for the treatment of Ebola virus disease.Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular EntryDiscovery of an antibody for pan-ebolavirus therapyIn silico-based vaccine design against Ebola virus glycoproteinConsiderations for Use of Investigational Drugs in Public Health Emergencies.Human antibody repertoire after VSV-Ebola vaccination identifies novel targets and virus-neutralizing IgM antibodies.Potent neutralizing monoclonal antibodies against Ebola virus infectionAntibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding SitePost-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic.Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1.Clinical Evaluation of Ebola Virus Disease Therapeutics.Initiating a watch list for Ebola virus antibody escape mutations.Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture.Discovering Drugs for the Treatment of Ebola Virus.Epitope mapping of Ebola virus dominant and subdominant glycoprotein epitopes facilitates construction of an epitope-based DNA vaccine able to focus the antibody response in mice.Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.Analysis of Ebola virus polymerase domains to find strain-specific differences and to gain insight on their pathogenicity.Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus.An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein.[Epidemiological aspects of Ebola virus disease in Guinea (december 2013-april 2016)].B and T Cell Epitope-Based Peptides Predicted from Evolutionarily Conserved and Whole Protein Sequences of Ebola Virus as Vaccine Targets.A Biologically-validated HCV E1E2 Heterodimer Structural Model.Combinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding.Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-Domain Antibodies.Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins.Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region.Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to ProtectionCandidate medical countermeasures targeting Ebola virus cell entryGrowth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry PathwayMultifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus GlycoproteinGeneration of therapeutic antisera for emerging viral infectionsAntibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors
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P2860
Mechanism of Binding to Ebola Virus Glycoprotein by the ZMapp, ZMAb, and MB-003 Cocktail Antibodies.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@ast
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@en
type
label
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@ast
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@en
prefLabel
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@ast
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@en
P2093
P2860
P356
P1433
P1476
Mechanism of Binding to Ebola ...... nd MB-003 Cocktail Antibodies.
@en
P2093
Benjamin J Doranz
Christopher Bryan
Edgar Davidson
Jennifer M Pfaff
Joseph B Rucker
Manu Mabila
Rachel H Fong
Trevor Barnes
P2860
P304
10982-10992
P356
10.1128/JVI.01490-15
P407
P577
2015-08-26T00:00:00Z