Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair.
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FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stressMus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complexHold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage.Combined fluorescent and electron microscopic imaging unveils the specific properties of two classes of meiotic crossovers.Msh4 and Msh5 function in SC-independent chiasma formation during the streamlined meiosis of TetrahymenaRad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombinationA physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repairRoles for mismatch repair family proteins in promoting meiotic crossing over.RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cellsResolution of single and double Holliday junction recombination intermediates by GEN1.Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosisResolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.When genome integrity and cell cycle decisions collide: roles of polo kinases in cellular adaptation to DNA damage.Holliday junction resolvases.An Overview of the Molecular Mechanisms of Recombinational DNA Repair.Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability.MUS81-EME2 promotes replication fork restart.Control of Mus81 nuclease during the cell cycle.Reduced kinase activity of polo kinase Cdc5 affects chromosome stability and DNA damage response in S. cerevisiae.Glutathione peroxidase activity is neuroprotective in models of Huntington's disease.Cdc14 targets the Holliday junction resolvase Yen1 to the nucleus in early anaphaseTemporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage.The Slx4-Dpb11 scaffold complex: coordinating the response to replication fork stalling in S-phase and the subsequent mitosis.A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication.Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein.Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.Analysis of crossover breakpoints yields new insights into the nature of the gene conversion events associated with large NF1 deletions mediated by nonallelic homologous recombination.Resolution of D-loop Structures through Holliday Junction IntermediatesMUS81:EME1;EME2 cleaves D-loopPopulation-specific differences in gene conversion patterns between human SUZ12 and SUZ12P are indicative of the dynamic nature of interparalog gene conversion.The nucleolytic resolution of recombination intermediates in yeast mitotic cells.Mus81-Mms4 and Yen1 resolve a novel anaphase bridge formed by noncanonical Holliday junctions.Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics.
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P2860
Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair.
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2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
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name
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@ast
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@en
type
label
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@ast
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@en
prefLabel
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@ast
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@en
P2093
P2860
P356
P1476
Mus81-Mms4 functions as a sing ...... in recombinational DNA repair.
@en
P2093
Erin K Schwartz
James E Evans
Kirk T Ehmsen
William D Wright
P2860
P304
P356
10.1128/MCB.00547-12
P407
P577
2012-05-29T00:00:00Z