Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin.

Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin.

Item
http://www.wikidata.org/entity/Q36210918
Seven non-contiguous intracellular residues of the lutropin/choriogonadotropin receptor dictate the rate of agonist-induced internalization and its sensitivity to non-visual arrestinsEndosome maturationGIPC binds to the human lutropin receptor (hLHR) through an unusual PDZ domain binding motif, and it regulates the sorting of the internalized human choriogonadotropin and the density of cell surface hLHRDecreased degradation of internalized follicle-stimulating hormone caused by mutation of aspartic acid 6.30(550) in a protein kinase-CK2 consensus sequence in the third intracellular loop of human follicle-stimulating hormone receptor.A constitutively active mutant of the human lutropin receptor (hLHR-L457R) escapes lysosomal targeting and degradation.Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathwayTransport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes.Binding and internalization in vivo of [125I]hCG in Leydig cells of the rat.Pathways of internalization of the hCG/LH receptor: immunoelectron microscopic studies in Leydig cells and transfected L-cells.Mutations of the second extracellular loop of the human lutropin receptor emphasize the importance of receptor activation and de-emphasize the importance of receptor phosphorylation in agonist-induced internalization.Multiple distant amino acid residues present in the serpentine region of the follitropin receptor modulate the rate of agonist-induced internalization.The rate of internalization of the gonadotropin receptors is greatly affected by the origin of the extracellular domain.Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization.Differences in internalization and intracellular processing of interleukin-1 associated with the two forms of interleukin-1 receptor found in B-cells and T-cells.The role of luteinizing hormone and prolactin in the regulation of insulin receptors in Leydig cells of the adult rat.Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the Lutropin/Choriogonadotropin receptor.Intracellular Trafficking of Gonadotropin Receptors in Health and Disease.
P2860

Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin.

Item
http://www.wikidata.org/entity/Q36210918
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@ast
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@en
type
label
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@ast
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@en
prefLabel
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@ast
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Lysosomal accumulation of the ...... s of human choriogonadotropin.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932