GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis.
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The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chainMitochondrial Stat3, the Need for Design ThinkingContribution of chaperones to STAT pathway signaling.The role of necroptosis in neurosurgical diseasesMitoneet mediates TNFα-induced necroptosis promoted by exposure to fructose and ethanol.Regulation and function of signal transducer and activator of transcription 3.Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunctionBiogenic selenium nanoparticles induce ROS-mediated necroptosis in PC-3 cancer cells through TNF activation.Necroptotic signaling in adaptive and innate immunity.Vaccinia virus induces rapid necrosis in keratinocytes by a STAT3-dependent mechanismToward a new STATe: the role of STATs in mitochondrial function.Gallic acid induces necroptosis via TNF-α signaling pathway in activated hepatic stellate cells.Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophagesGranulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer.Stat3: friend or foe in colitis and colitis-associated cancer?Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashionThe control of reactive oxygen species production by SHP-1 in oligodendrocytesInhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline.Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.Tumor-derived mutations in the gene associated with retinoid interferon-induced mortality (GRIM-19) disrupt its anti-signal transducer and activator of transcription 3 (STAT3) activity and promote oncogenesis.New tricks from an old dog: mitochondrial redox signaling in cellular inflammation.STAT3 signal that mediates the neural plasticity is involved in willed-movement training in focal ischemic ratsSmall interfering RNA survivin and GRIM-19 co-expression salmonella plasmid inhibited the growth of laryngeal cancer cells in vitro and in vivo.Evidence for site-specific occupancy of the mitochondrial genome by nuclear transcription factors.Loss of STAT3 in mouse embryonic fibroblasts reveals its Janus-like actions on mitochondrial function and cell viability.FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumorsGRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation.Multi-tasking: nuclear transcription factors with novel roles in the mitochondria.New components of the necroptotic pathway.Dancing rhinos in stilettos: The amazing saga of the genomic and nongenomic actions of STAT3 in the heart.Oxidative metabolism in cancer: A STAT affair?STAT3 and metabolism: how many ways to use a single molecule?STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemia.STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug ResistanceRip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafishNon-canonical Stat3 signaling in cancer.STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy.Death receptor 3 mediates necroptotic cell death.Sodium orthovanadate suppresses palmitate-induced cardiomyocyte apoptosis by regulation of the JAK2/STAT3 signaling pathway.Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo.
P2860
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P2860
GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@ast
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@en
type
label
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@ast
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@en
prefLabel
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@ast
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@en
P2860
P356
P1476
GRIM-19-mediated translocation ...... y for TNF-induced necroptosis.
@en
P2093
John G Pastorino
Nataly Shulga
P2860
P304
P356
10.1242/JCS.103093
P407
P577
2012-03-05T00:00:00Z