Glucuronidation and its role in regulation of biological activity of drugs.
about
Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroidsGlucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomesDiclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolitesMolecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificityPharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria.Urinary conjugated α-tocopheronolactone--a biomarker of oxidative stress in children with type 1 diabetes.In vitro and in vivo metabolic studies of phospho-aspirin (MDC-22)Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.Physiological and pharmacological significance of glutathione-conjugate transport.Idiosyncratic liver toxicity of nonsteroidal antiinflammatory drugs: molecular mechanisms and pathology.Glucuronide and Sulfate Conjugates of Bisphenol A: Chemical Synthesis and Correlation Between Their Urinary Levels and Plasma Bisphenol A Content in Voluntary Human Donors.Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury.In vitro methods for assessing human hepatic drug metabolism: their use in drug development.Characterization of uronate dehydrogenases catalysing the initial step in an oxidative pathway.Structure and function of uridine diphosphate glucuronosyltransferases.Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism.Acyl-CoA binding and acylation of UDP-glucuronosyltransferase isoforms of rat liver: their effect on enzyme activity.Improved Synthesis of the C-Glucuronide/Glycoside of 4-Hydroxybenzylretinone (4-HBR)Constitutive and inducible expression of drug metabolizing enzymes in cultured human keratinocytes.Glucuronidation of diflunisal in liver and kidney microsomes of rat and man.Intraluminal calcium of the liver endoplasmic reticulum stimulates the glucuronidation of p-nitrophenol.Urinary metabolites of leukotriene B4 in the human subject.NMR and QSAR studies on the transacylation reactivity of model 1beta-O-acyl glucuronides. I: design, synthesis and degradation rate measurement.Expression of the human UDP-glucuronosyltransferase UGT1*6 in Escherichia coli. Influence of bacterial signal peptides on the production and localization of the recombinant protein.Pharmacokinetics, metabolism, and excretion of nefopam, a dual reuptake inhibitor in healthy male volunteers.
P2860
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P2860
Glucuronidation and its role in regulation of biological activity of drugs.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Glucuronidation and its role in regulation of biological activity of drugs.
@ast
Glucuronidation and its role in regulation of biological activity of drugs.
@en
type
label
Glucuronidation and its role in regulation of biological activity of drugs.
@ast
Glucuronidation and its role in regulation of biological activity of drugs.
@en
prefLabel
Glucuronidation and its role in regulation of biological activity of drugs.
@ast
Glucuronidation and its role in regulation of biological activity of drugs.
@en
P1476
Glucuronidation and its role in regulation of biological activity of drugs.
@en
P2093
P356
10.1146/ANNUREV.PA.32.040192.000325
P577
1992-01-01T00:00:00Z