Functional importance of Dicer protein in the adaptive cellular response to hypoxia. - Wikidata - awgldk - TriplyDB

Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

http://www.wikidata.org/entity/Q36217312

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Role of Extracellular Vesicles and microRNAs on Dysfunctional Angiogenesis during Preeclamptic Pregnancies MicroRNA in radiotherapy: miRage or miRador?miRNA Deregulation in Cancer Cells and the Tumor Microenvironment Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease.Posttranscriptional and transcriptional regulation of endothelial nitric-oxide synthase during hypoxia: the role of microRNAs.Identification and characterization of Dicer1e, a Dicer1 protein variant, in oral cancer cells.HypoxamiR regulation and function in ischemic cardiovascular diseases.Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.Hypoxia represses microRNA biogenesis proteins in breast cancer cells.Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop.Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells.MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1 Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.Ablation of Dicer leads to widespread perturbation of signaling pathways.Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis Active stabilization of human endothelial nitric oxide synthase mRNA by hnRNP E1 protects against antisense RNA and microRNAs.Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α.In vivo delivery of miRNAs for cancer therapy: challenges and strategies.Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia.Discerning functional hierarchies of microRNAs in pulmonary hypertension.Dynamin 2 along with microRNA-199a reciprocally regulate hypoxia-inducible factors and ovarian cancer metastasis.Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain.Epigenetic regulation of hypoxia inducible factor in diseases and therapeutics.Hypoxia: a master regulator of microRNA biogenesis and activity Competition and collaboration between RNA-binding proteins and microRNAs.Regulation of miR-17-92a cluster processing by the microRNA binding protein SND1.Advances, nuances, and potential pitfalls when exploiting the therapeutic potential of RNA interference.Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing.Stress response factors as hub-regulators of microRNA biogenesis: implication to the diseased heart.MicroRNA-185 inhibits angiogenesis in human microvascular endothelial cells through targeting stromal interaction molecule 1.Dicer mediating the expression of miR-143 and miR-155 regulates hexokinase II associated cellular response to hypoxia.Metabolic zonation of the liver: The oxygen gradient revisited.Dissecting microRNA dysregulation in age-related macular degeneration: new targets for eye gene therapy.The epigenetic regulation of Dicer and microRNA biogenesis by Panobinostat.Reduced miR-659-3p Levels Correlate with Progranulin Increase in Hypoxic Conditions: Implications for Frontotemporal Dementia

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Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

http://www.wikidata.org/entity/Q36217312

description

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name

Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

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Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

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type

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Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

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Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

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prefLabel

Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

@ast

Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

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JBC.M112.373365

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Journal of Biological Chemistry

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Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

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Albert K Y Tsui

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G Brett Robb

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H S Jeffrey Man

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Helena Dhamko

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J J David Ho

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Jeff Z He

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Jenny Jing Wang

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Julie L Metcalf

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Maria Chalsev

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Matthew S Yan

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P2860

MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia

Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1

Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels

miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

The dicey role of Dicer: implications for RNAi therapy

MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3

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