Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic Semliki Forest virus encoding IL-12.
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Interleukin 12: still a promising candidate for tumor immunotherapy?Alphavirus-based vaccines4-1BB Agonists: Multi-Potent Potentiators of Tumor ImmunityMesenchymal stem cells genetically modified by lentivirus-mediated interleukin-12 inhibit malignant ascites in mice.Agonist antibodies to TNFR molecules that costimulate T and NK cellsFocusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice.Therapeutic effects of bone marrow mesenchymal stem cells expressing interleukin-12 in mice bearing malignant ascites tumor.Virotherapy, gene transfer and immunostimulatory monoclonal antibodies.Self-replicating alphavirus RNA vaccines.Intratumoral immunotherapy for melanoma.Immunological landscape and immunotherapy of hepatocellular carcinoma.Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.Intratumoral Delivery of Immunotherapy-Act Locally, Think Globally.The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome.Functional expression of CD137 (4-1BB) on T helper follicular cells.Cardiotrophin-1 determines liver engraftment of syngenic colon carcinoma cells through an immune system-mediated mechanismRouting cancer immunology and immunotherapy from the lab to the clinic 4-5 th March 2014, Center for Applied Medical Research and University Clinic, Pamplona, Spain.Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity
P2860
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P2860
Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic Semliki Forest virus encoding IL-12.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@ast
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@en
type
label
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@ast
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@en
prefLabel
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@ast
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@en
P2093
P2860
P356
P1433
P1476
Immunotherapeutic synergy betw ...... i Forest virus encoding IL-12.
@en
P2093
Cristian Smerdou
Ignacio Melero
Jaione Bezunartea
José I Quetglas
Juan Dubrot
Miguel F Sanmamed
Sandra Hervas-Stubbs
P2860
P304
P356
10.1038/MT.2012.56
P577
2012-06-26T00:00:00Z