Molecular and ultrastructural defects in a Drosophila myosin heavy chain mutant: differential effects on muscle function produced by similar thick filament abnormalities.
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Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in DrosophilaAssembly of the giant protein projectin during myofibrillogenesis in Drosophila indirect flight musclesSarcomere formation occurs by the assembly of multiple latent protein complexesIfm(2)2 is a myosin heavy chain allele that disrupts myofibrillar assembly only in the indirect flight muscle of Drosophila melanogasterMyosin functional domains encoded by alternative exons are expressed in specific thoracic muscles of DrosophilaMapping interactions between myosin relay and converter domains that power muscle function.CF2 represses Actin 88F gene expression and maintains filament balance during indirect flight muscle development in Drosophila.Paramyosin phosphorylation site disruption affects indirect flight muscle stiffness and power generation in Drosophila melanogasterCo-localization to chromosome bands 99E1-3 of the Drosophila melanogaster myosin light chain-2 gene and a haplo-insufficient locus that affects flight behaviorRecovery of dominant, autosomal flightless mutants of Drosophila melanogaster and identification of a new gene required for normal muscle structure and function.Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight abilityDetermining structure/function relationships for sarcomeric myosin heavy chain by genetic and transgenic manipulation of Drosophila.Alternative N-terminal regions of Drosophila myosin heavy chain tune muscle kinetics for optimal power output.The role of evolutionarily conserved sequences in alternative splicing at the 3' end of Drosophila melanogaster myosin heavy chain RNASuppression of muscle hypercontraction by mutations in the myosin heavy chain gene of Drosophila melanogaster.Green fluorescent protein tagging Drosophila proteins at their native genomic loci with small P elementsMolecular biology of human muscle disease.The Regulation of Muscle Structure and Metabolism by Mio/dChREBP in Drosophila.Alternative relay and converter domains tune native muscle myosin isoform function in Drosophila.Myosin heavy chain isoforms regulate muscle function but not myofibril assembly.Muscle-specific accumulation of Drosophila myosin heavy chains: a splicing mutation in an alternative exon results in an isoform substitution.Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length.Invertebrate muscles: muscle specific genes and proteins.Myosin mRNA accumulation and myofibrillogenesis at the myotendinous junction of stretched muscle fibersTransformation of Drosophila melanogaster with the wild-type myosin heavy-chain gene: rescue of mutant phenotypes and analysis of defects caused by overexpression.Both synchronous and asynchronous muscle isoforms of projectin (the Drosophila bent locus product) contain functional kinase domains.Specific myosin heavy chain mutations suppress troponin I defects in Drosophila musclesNebulin regulates the assembly and lengths of the thin filaments in striated muscleDrosophila paramyosin is important for myoblast fusion and essential for myofibril formation.A Failure to Communicate: MYOSIN RESIDUES INVOLVED IN HYPERTROPHIC CARDIOMYOPATHY AFFECT INTER-DOMAIN INTERACTION.Myosin light chain-2 mutation affects flight, wing beat frequency, and indirect flight muscle contraction kinetics in Drosophila.The Drosophila Z-disc protein Z(210) is an adult muscle isoform of Zasp52, which is required for normal myofibril organization in indirect flight muscles.Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function.A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in DrosophilaAlternative versions of the myosin relay domain differentially respond to load to influence Drosophila muscle kinetics.Assembly of thick filaments and myofibrils occurs in the absence of the myosin head.Alternative mechanisms for talin to mediate integrin functionOverexpression of troponin T in Drosophila muscles causes a decrease in the levels of thin-filament proteins.Analysis of Drosophila paramyosin: identification of a novel isoform which is restricted to a subset of adult muscles.Variable N-terminal regions of muscle myosin heavy chain modulate ATPase rate and actin sliding velocity.
P2860
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P2860
Molecular and ultrastructural defects in a Drosophila myosin heavy chain mutant: differential effects on muscle function produced by similar thick filament abnormalities.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Molecular and ultrastructural ...... thick filament abnormalities.
@ast
Molecular and ultrastructural ...... thick filament abnormalities.
@en
type
label
Molecular and ultrastructural ...... thick filament abnormalities.
@ast
Molecular and ultrastructural ...... thick filament abnormalities.
@en
prefLabel
Molecular and ultrastructural ...... thick filament abnormalities.
@ast
Molecular and ultrastructural ...... thick filament abnormalities.
@en
P2860
P356
P1476
Molecular and ultrastructural ...... thick filament abnormalities.
@en
P2093
P T O'Donnell
S I Bernstein
P2860
P304
P356
10.1083/JCB.107.6.2601
P407
P433
P577
1988-12-01T00:00:00Z