Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells
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Regulation of embryonic cell adhesion by the prion proteinA camelid anti-PrP antibody abrogates PrP replication in prion-permissive neuroblastoma cell linesLysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulationConversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteinsPrionsUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesRegulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant miceLoss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1Prion diseases: dynamics of the infection and properties of the bistable transition.Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cellsCritical significance of the region between Helix 1 and 2 for efficient dominant-negative inhibition by conversion-incompetent prion proteinThe membrane environment of endogenous cellular prion protein in primary rat cerebellar neuronsLive imaging of prions reveals nascent PrPSc in cell-surface, raft-associated amyloid strings and websTwo Creutzfeldt-Jakob disease agents reproduce prion protein-independent identities in cell cultures.The multivesicular body is the major internal site of prion conversion.Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation.Mapping the prion protein using recombinant antibodies.Cellular biology of prion diseases.Neurodegeneration in humans caused by prionsOxidation of Helix-3 methionines precedes the formation of PK resistant PrP.A receptor for infectious and cellular prion protein.Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoformRapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassaysConservation of infectivity in purified fibrillary extracts of scrapie-infected hamster brain after sequential enzymatic digestion or polyacrylamide gel electrophoresisDominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion proteinAcquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylationScrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody.Caveolae structure and functionOverexpression of nonconvertible PrPc delta114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation.Characterization of the prion protein in human urine.Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting diseaseSpecies specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrierPrions.Variant Creutzfeldt-Jakob disease: risk of transmission by blood transfusion and blood therapies.Scrapie prions selectively modify the stress response in neuroblastoma cellsA quantitative proteomic approach to prion disease biomarker research: delving into the glycoproteome.The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPScMolecular origin of Gerstmann-Sträussler-Scheinker syndrome: insight from computer simulation of an amyloidogenic prion peptide.Prion protein biosynthesis and its emerging role in neurodegeneration.
P2860
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P2860
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Scrapie and cellular prion pro ...... and topology in cultured cells
@ast
Scrapie and cellular prion pro ...... and topology in cultured cells
@en
type
label
Scrapie and cellular prion pro ...... and topology in cultured cells
@ast
Scrapie and cellular prion pro ...... and topology in cultured cells
@en
prefLabel
Scrapie and cellular prion pro ...... and topology in cultured cells
@ast
Scrapie and cellular prion pro ...... and topology in cultured cells
@en
P2093
P2860
P356
P1476
Scrapie and cellular prion pro ...... and topology in cultured cells
@en
P2093
P2860
P304
P356
10.1083/JCB.110.3.743
P407
P577
1990-03-01T00:00:00Z