In vivo high-throughput profiling of CRISPR-Cpf1 activity.
about
sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity.Functional interrogation of non-coding DNA through CRISPR genome editing.CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools.dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.Immunity to CRISPR Cas9 and Cas12a therapeutics.CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing.Efficient targeted DNA editing and replacement in Chlamydomonas reinhardtii using Cpf1 ribonucleoproteins and single-stranded DNA.Engineered Cpf1 variants with altered PAM specificities.Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.FnCpf1: a novel and efficient genome editing tool for Saccharomyces cerevisiae.The Conspicuity of CRISPR-Cpf1 System as a Significant Breakthrough in Genome Editing.Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.Cas9, Cpf1 and C2c1/2/3-What's next?Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1.CRISPR/Cpf1 enables fast and simple genome editing of Saccharomyces cerevisiae.Marker-free coselection for CRISPR-driven genome editing in human cells.Efficient and Scalable Precision Genome Editing in Staphylococcus aureus through Conditional Recombineering and CRISPR/Cas9-Mediated Counterselection.A highly specific SpCas9 variant is identified by in vivo screening in yeast.The promise and peril of CRISPR gene drives: Genetic variation and inbreeding may impede the propagation of gene drives based on the CRISPR genome editing technology.CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration.Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variantsExtension of the crRNA enhances Cpf1 gene editing in vitro and in vivoClass 2 CRISPR/Cas: an expanding biotechnology toolbox for and beyond genome editing
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P2860
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@ast
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@en
type
label
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@ast
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@en
prefLabel
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@ast
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@en
P2093
P2860
P50
P356
P1433
P1476
In vivo high-throughput profiling of CRISPR-Cpf1 activity.
@en
P2093
Hyun C Koh
Myungjae Song
Soobin Jung
Young-Mook Kang
P2860
P2888
P304
P356
10.1038/NMETH.4104
P577
2016-12-19T00:00:00Z