IL-25 regulates Th17 function in autoimmune inflammation. - Wikidata - awgldk - TriplyDB

IL-25 regulates Th17 function in autoimmune inflammation.

IL-25 regulates Th17 function in autoimmune inflammation.

http://www.wikidata.org/entity/Q36228942

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The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings APC-derived cytokines and T cell polarization in autoimmune inflammation Regulation of Th2 Cell Immunity by Dendritic Cells Regulation of IL-17 in autoimmune diseases by transcriptional factors and microRNAs Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection.The microbiota and immune response during Clostridium difficile infection.Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE)Interleukin-25 expressed by brain capillary endothelial cells maintains blood-brain barrier function in a protein kinase Cepsilon-dependent manner.IL-17 signaling-independent central nervous system autoimmunity is negatively regulated by TGF-beta.Autoimmune T cell responses in the central nervous system Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo.More stories on Th17 cells.Th17 cells: effector T cells with inflammatory properties.Activated IL-23/IL-17 pathway closely correlates with increased Foxp3 expression in livers of chronic hepatitis B patients.Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech.Molecular analysis of interleukin-25 exons 1 and 2 and its serum levels in Iranian patients with multiple sclerosis.IL-23/IL-17 axis in IBD.Differential dose effects of recombinant IL-25 on the development of dextran sulfate sodium-induced colitis.IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils Critical role of IL-25 in nematode infection-induced alterations in intestinal function.Colitis and intestinal inflammation in IL10-/- mice results from IL-13Rα2-mediated attenuation of IL-13 activity.Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia.Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.IL-25 inhibits atherosclerosis development in apolipoprotein E deficient mice ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes IL-25 induces M2 macrophages and reduces renal injury in proteinuric kidney disease More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model T cell subsets and their signature cytokines in autoimmune and inflammatory diseases.Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice The current concept of T (h) 17 cells and their expanding role in systemic lupus erythematosus.IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner.

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P2860

IL-25 regulates Th17 function in autoimmune inflammation.

http://www.wikidata.org/entity/Q36228942

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IL-25 regulates Th17 function in autoimmune inflammation.

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IL-25 regulates Th17 function in autoimmune inflammation.

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IL-25 regulates Th17 function in autoimmune inflammation.

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IL-25 regulates Th17 function in autoimmune inflammation.

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IL-25 regulates Th17 function in autoimmune inflammation.

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Journal of Experimental Medicine

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IL-25 regulates Th17 function in autoimmune inflammation.

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Alexander M Owyang

http://www.w3.org/2001/XMLSchema#string

Barbara Joyce-Shaikh

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Claire L Langrish

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Daniel J Cua

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Daniel M Gorman

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Frank Brombacher

http://www.w3.org/2001/XMLSchema#string

Melanie A Kleinschek

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Robert A Kastelein

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Stephen D Hurst

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Terrill McClanahan

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P2860

IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract

Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Alternative activation of macrophages

IL-13 effector functions

Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activation

Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production

Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in mice

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161-170

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10.1084/JEM.20061738

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1

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204

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6601286

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17200411

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2118427

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