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Control of the thymic medulla and its influence on αβT-cell developmentThe Contribution of Chemokines and Migration to the Induction of Central Tolerance in the ThymusThymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance InductionT Cell Adolescence: Maturation Events Beyond Positive SelectionElimination of self-reactive T cells in the thymus: a timeline for negative selectionAntigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medullaCCR6 supports migration and differentiation of a subset of DN1 early thymocyte progenitors but is not required for thymic nTreg developmentB-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cellsT Cell Adaptive Immunity Proceeds through Environment-Induced Adaptation from the Exposure of Cryptic Genetic VariationRecent thymic emigrants are preferentially incorporated only into the depleted T-cell pool.Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns.Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantationOverlapping and asymmetric functions of TCR signaling during thymic selection of CD4 and CD8 lineagesImpaired thymic selection and abnormal antigen-specific T cell responses in Foxn1(Δ/Δ) mutant mice.Maturation-dependent licensing of naive T cells for rapid TNF production.Thymic emigration: when and how T cells leave home.Human T-Cell Development and Thymic Egress: An Infectious Disease PerspectiveThe molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytesBoth retention and recirculation contribute to long-lived regulatory T-cell accumulation in the thymus.Developmental dynamics of post-selection thymic DN iNKT.Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage.The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medullaNeural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junctionTracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombinationThymic T-cell development in allogeneic stem cell transplantationTranscription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene.Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment.T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse.Lipid phosphate phosphatase 3 enables efficient thymic egress.Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision.Post-thymic maturation: young T cells assert their individuality.Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation.Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells.The Neonatal CD4+ T Cell Response to a Single Epitope Varies in Genetically Identical MiceDecision checkpoints in the thymus.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Thymic emigration revisited
@ast
Thymic emigration revisited
@en
type
label
Thymic emigration revisited
@ast
Thymic emigration revisited
@en
prefLabel
Thymic emigration revisited
@ast
Thymic emigration revisited
@en
P2093
P2860
P356
P1476
Thymic emigration revisited
@en
P2093
Kristin A Hogquist
Matthew S Wilken
Tom M McCaughtry
P2860
P304
P356
10.1084/JEM.20070601
P407
P577
2007-10-01T00:00:00Z