CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance.
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IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansUnbalanced Immune System: Immunodeficiencies and AutoimmunityUpdate on the hyper immunoglobulin M syndromesAutoimmunity in primary T-cell immunodeficiencies.Autoimmune manifestations in common variable immunodeficiency.Autoimmunity in primary immune deficiency: taking lessons from our patients.An innate path to human B cell tolerance.Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance.Potential roles of activation-induced cytidine deaminase in promotion or prevention of autoimmunity in humansCD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells.Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans.Activation-induced cytidine deaminase mediates central tolerance in B cells.The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humansImmunoglobulin M levels inversely correlate with CD40 ligand promoter methylation in patients with primary biliary cirrhosis.B cells and autoimmunity.Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapyAutoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophagesLentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development.Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatmentBCR and co-receptor crosstalk facilitate the positive selection of self-reactive transitional B cells.B Cells, Antibodies, and More.Warts and all: human papillomavirus in primary immunodeficiencies.Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloningAccumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells.Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.Specific peripheral B cell tolerance defects in patients with multiple sclerosisProposed therapies in primary biliary cholangitis.Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications.MHC class II antigen presentation and immunological abnormalities due to deficiency of MHC class II and its associated genes.CVID-associated TACI mutations affect autoreactive B cell selection and activation.Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases.TLR7 and TLR9 in SLE: when sensing self goes wrong.The role of B lymphocyte stimulator in B cell biology: implications for the treatment of lupus.The hyper IgM syndromes.Immunoglobulin class switch recombination deficiency type 1 or CD40 ligand deficiency: from bedside to bench and back again.Germinal centers and autoimmune disease in humans and mice.
P2860
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P2860
CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@ast
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@en
type
label
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@ast
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@en
prefLabel
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@ast
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@en
P2093
P2860
P356
P1476
CD40 ligand and MHC class II e ...... n peripheral B cell tolerance.
@en
P2093
Eric Meffre
Hans D Ochs
Isabelle Isnardi
Maxime Hervé
Yen-shing Ng
P2860
P304
P356
10.1084/JEM.20062287
P407
P577
2007-06-11T00:00:00Z