about
Chemical probes that competitively and selectively inhibit Stat3 activationAPE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalA Jurkat transcriptional reporter cell line for high-throughput analysis of the nuclear factor-kappaB signaling pathway.Identification of small molecule compounds that inhibit the HIF-1 signaling pathwayE2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancerA general method for discovering inhibitors of protein-DNA interactions using photonic crystal biosensorsRegulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer.In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer.Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform.Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model.Free radical theory of autoimmunityDown-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells.Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesisExpression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression.Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes.Embryonic stem cell preconditioned microenvironment suppresses tumorigenic properties in breast cancerAntisense, RNAi, and gene silencing strategies for therapy: mission possible or impossible?Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinomaFOXM1 and its oncogenic signaling in pancreatic cancer pathogenesisSignal transducer and activator of transcription 3 inhibitors: a patent review.Recent patents on therapeutic applications of the transcription factor decoy approach.Cell death in NF-kappaB-dependent tumour cell lines as a result of NF-kappaB trapping by linker-modified hairpin decoy oligonucleotide.Simultaneous targeted inhibition of Sox2-Oct4 transcription factors using decoy oligodeoxynucleotides to repress stemness properties in mouse embryonic stem cells.Combined effect of dehydroxymethylepoxyquinomicin and gemcitabine in a mouse model of liver metastasis of pancreatic cancer.Antisense oligodeoxynucleotide targeting HER2 mRNA sensitized docetaxel in breast cancer treatment.STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Targeting transcription factors for cancer therapy.
@ast
Targeting transcription factors for cancer therapy.
@en
type
label
Targeting transcription factors for cancer therapy.
@ast
Targeting transcription factors for cancer therapy.
@en
prefLabel
Targeting transcription factors for cancer therapy.
@ast
Targeting transcription factors for cancer therapy.
@en
P356
P1476
Targeting transcription factors for cancer therapy.
@en
P2093
David J Tweardy
Michele S Redell
P304
P356
10.2174/1381612054546699
P577
2005-01-01T00:00:00Z