Physiology and pharmacology of two-pore domain potassium channels.
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TWIK-1 two-pore domain potassium channels change ion selectivity and conduct inward leak sodium currents in hypokalemiaA human TREK-1/HEK cell line: a highly efficient screening tool for drug development in neurological diseasesA splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channelsLinolenic acid provides multi-cellular protective effects after photothrombotic cerebral ischemia in ratsAKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channelsTASK channels contribute to neuroprotective action of inhalational anesthetics.The role of pH-sensitive TASK channels in central respiratory chemoreception.Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold.Deafness associated changes in expression of two-pore domain potassium channels in the rat cochlear nucleus.TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system.Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact.Two-pore K+ channels, NO and metabolic inhibition.Novel neuroprotectant chiral 3-n-butylphthalide inhibits tandem-pore-domain potassium channel TREK-1Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current.The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia.Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept.Colitis decreases mechanosensitive K2P channel expression and function in mouse colon sensory neuronsA role for two-pore K⁺ channels in modulating Na⁺ absorption and Cl⁻ secretion in normal human bronchial epithelial cellsTWIK-Related Spinal Cord K⁺ Channel Expression Is Increased in the Spinal Dorsal Horn after Spinal Nerve Ligation.Ability to induce atrial fibrillation in the peri-operative period is associated with phosphorylation-dependent inhibition of TWIK protein-related acid-sensitive potassium channel 1 (TASK-1)Molecular and cellular limits to somatosensory specificity.Roles of TRESK, a novel two-pore domain K+ channel, in pain pathway and general anesthesia.Arachidonic acid and ion channels: an updateGABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels.The Inhibition of TREK2 Channel by an Oxidizing Agent, 5,5'-dithio-bis (2-nitrobenzoic acid), via Interaction with the C-terminus Distal to the 353rd Amino Acid.Identification and functional characterization of ion channels in CD34(+) hematopoietic stem cells from human peripheral blood.Patents related to therapeutic activation of K(ATP) and K(2P) potassium channels for neuroprotection: ischemic/hypoxic/anoxic injury and general anesthetics.Classification of 2-pore domain potassium channels based on rectification under quasi-physiological ionic conditions.Effects of acidic pH on voltage-gated ion channels in rat trigeminal mesencephalic nucleus neurons.Ion channels as novel therapeutic targets in the treatment of pain.Trafficking of neuronal two pore domain potassium channels.K(+) channels as therapeutic targets in oncology.Steroidogenesis-adrenal cell signal transduction.The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration.Much more than a leak: structure and function of K₂p-channels.Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina.Stable cell line of human SH-SY5Y uniformly expressing TWIK-related acid-sensitive potassium channel and eGFP fusion.Potassium channel silencing by constitutive endocytosis and intracellular sequestration.Expression of TASK-2 and its upregulation by B cell receptor stimulation in WEHI-231 mouse immature B cells.AMP-activated protein kinase inhibits TREK channels.
P2860
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P2860
Physiology and pharmacology of two-pore domain potassium channels.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Physiology and pharmacology of two-pore domain potassium channels.
@ast
Physiology and pharmacology of two-pore domain potassium channels.
@en
type
label
Physiology and pharmacology of two-pore domain potassium channels.
@ast
Physiology and pharmacology of two-pore domain potassium channels.
@en
prefLabel
Physiology and pharmacology of two-pore domain potassium channels.
@ast
Physiology and pharmacology of two-pore domain potassium channels.
@en
P356
P1476
Physiology and pharmacology of two-pore domain potassium channels.
@en
P2093
Donghee Kim
P304
P356
10.2174/1381612054546824
P577
2005-01-01T00:00:00Z