Drug-associated mitochondrial toxicity and its detection.
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Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes.Chemical cytometry quantitates superoxide levels in the mitochondrial matrix of single myoblasts.The role of toxicoproteomics in assessing organ specific toxicity.Mechanisms of MDMA (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage.Selectivity of TMC207 towards mycobacterial ATP synthase compared with that towards the eukaryotic homologue.Successful drug development despite adverse preclinical findings part 1: processes to address issues and most important findingsRespirometric Screening Technology for ADME-Tox studies.Strategies to reduce late-stage drug attrition due to mitochondrial toxicity.A pharmacogenomics primer.Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injuryAssessing neuronal bioenergetic status.Drug safety testing paradigm, current progress and future challenges: an overview.Mitochondrial dysfunction as a central event for mechanisms underlying insulin resistance: the roles of long chain fatty acids.Metabolic syndrome and the environmental pollutants from mitochondrial perspectives.Diarylquinolines, synthesis pathways and quantitative structure--activity relationship studies leading to the discovery of TMC207.Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis.Severe lactic acidosis associated with linezolid use in a patient with the mitochondrial DNA A2706G polymorphism.Study of the Effects of ATP Suppliers and Thiol Reductants on Toxicity of Pioglitazone in Isolated Rat Liver Mitochondria.Metabolic profiles show specific mitochondrial toxicities in vitro in myotube cells.Hepatitis E Virus Induces Hepatocyte Apoptosis via Mitochondrial Pathway in Mongolian Gerbils.Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability.Effects of mid-respiratory chain inhibition on mitochondrial function in vitro and in vivo.High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins
P2860
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P2860
Drug-associated mitochondrial toxicity and its detection.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Drug-associated mitochondrial toxicity and its detection.
@ast
Drug-associated mitochondrial toxicity and its detection.
@en
type
label
Drug-associated mitochondrial toxicity and its detection.
@ast
Drug-associated mitochondrial toxicity and its detection.
@en
prefLabel
Drug-associated mitochondrial toxicity and its detection.
@ast
Drug-associated mitochondrial toxicity and its detection.
@en
P356
P1476
Drug-associated mitochondrial toxicity and its detection.
@en
P2093
David E Amacher
P304
P356
10.2174/0929867054546663
P577
2005-01-01T00:00:00Z