A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis.
about
Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicryHLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseasesAntigen mimicry in autoimmune disease sharing of amino acid residues critical for pathogenic T cell activationMechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis.Molecular analysis of the helper T cell response in murine interstitial nephritis. T cells recognizing an immunodominant epitope use multiple T cell receptor V beta genes with similarities across CDR3.Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitisA small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11Binding of an invariant-chain peptide, CLIP, to I-A major histocompatibility complex class II molecules.Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC.Minimum structural requirements for peptide presentation by major histocompatibility complex class II molecules: implications in induction of autoimmunity.The lack of consensus for I-A(g7)-peptide binding motifs: is there a requirement for anchor amino acid side chains?Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitisEvidence that the autoimmune antigen myelin basic protein (MBP) Ac1-9 binds towards one end of the major histocompatibility complex (MHC) cleft.Quantitative analysis of peptides from myelin basic protein binding to the MHC class II protein, I-Au, which confers susceptibility to experimental allergic encephalomyelitis.Fine structure of a virus-encoded helper T-cell epitope expressed on FBL-3 tumor cells.Molecular mimicry: can epitope mimicry induce autoimmune disease?Manipulation of the Th1/Th2 cell balance: an approach to treat human autoimmune diseases?H-2-associated effects of flanking residues on the recognition of a permissive mycobacterial T-cell epitope.Immunomodulatory peptides with high binding affinity for class II MHC molecules for the prevention of graft-versus-host disease.Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptideSequence determinants of thermodynamic stability in a WW domain--an all-beta-sheet protein.Unique T-cell receptor junctional sequences found in multiple sclerosis and T-cells mediating experimental allergic encephalomyelitis.Identification of a cross-reactive self ligand in virus-mediated autoimmunity.Mechanisms and genetics of autoimmunity.Therapeutic peptides that block interaction of T cells with MHC in experimental allergic encephalomyelitis.Conformational studies of immunodominant myelin basic protein 1–11 analogues using NMR and molecular modeling
P2860
Q24563454-B7E0B72B-1E85-4A54-96CD-AC16B5CEB3B9Q24679388-3BC6451F-71EB-45C8-9924-A511318926ABQ30449280-6D250568-3243-47F0-93E9-E3DF2DF59FCCQ33713307-2DB9CDC7-A1D1-4701-BB37-6DA7B41F5A88Q34158991-54B9BECF-6C9D-481C-B615-83DD8511D311Q34234228-24B92521-03CC-4416-A916-53CF6FF9D6EBQ34798966-342B91A5-C74B-49A3-B9D8-E96BB65C7C43Q34871822-3445A06F-5D4E-4A63-8AA0-5E8ECABC7DEAQ34982932-77A7D53E-1DE9-473C-B69C-8FF009D7E071Q34999636-1649C086-699C-4FA2-9AEF-502C3692E9C4Q35557870-837F6435-80A5-474D-9AF4-A62DB3BADBEBQ36368042-2CBE8CCC-83F3-4714-A767-AA5865B812B9Q36400752-9239C0DF-0613-4A49-8E3D-5A6D38A9DE99Q36437858-5BF29626-A642-4195-9BE7-8AE5DE70B313Q40042778-343CA8A2-6001-4DE5-B711-3DAC63F47339Q40653042-321F00F8-7C2C-4ABF-BB1C-4B635F6F9CB3Q41167186-066631E5-A8D0-4610-A7B5-04D9EA9B2689Q41292354-7EE1DC91-79DB-409C-9F00-89AE22676F6BQ41342013-0B217ABA-0273-4C4E-A7C7-793A3E6A684FQ41990602-8DC4D66D-E8D2-49CC-96FF-3533E222E18CQ42635868-96E4084C-EA4C-4052-AAD1-D302B55CB32EQ43643623-C1715659-49B4-4E37-A22B-E83517A36739Q45746928-7B7C63F0-345A-4E90-84B2-D551CECAAA54Q46133590-AF720F1C-6B22-4E76-BE15-6A3844CFD6FFQ46583951-5BB55E5C-F866-4940-864D-788302C4D807Q57594206-4A9A83FB-05B8-48AD-AD23-8BA89E0365E0
P2860
A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@ast
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@en
type
label
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@ast
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@en
prefLabel
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@ast
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@en
P2093
P2860
P356
P1476
A polyalanine peptide with onl ...... autoimmune encephalomyelitis.
@en
P2093
McDevitt HO
Pearson CI
Steinman L
P2860
P304
P356
10.1084/JEM.176.2.605
P407
P577
1992-08-01T00:00:00Z