Peptide-induced conformational changes in class I heavy chains alter major histocompatibility complex recognition.
about
Influence of dominant HIV-1 epitopes on HLA-A3/peptide complex formation.Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides.H-2Dd exploits a four residue peptide binding motif.Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residuesAnalysis of the structure of empty and peptide-loaded major histocompatibility complex molecules at the cell surface.MHC class I molecules form ternary complexes with calnexin and TAP and undergo peptide-regulated interaction with TAP via their extracellular domains.Peptide-independent recognition by alloreactive cytotoxic T lymphocytes (CTL).Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes.A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptidesContribution of mass spectrometry-based proteomics to immunology.The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand.Mechanism of cellular rejection in transplantationInsights into MHC class I antigen processing gained from large-scale analysis of class I ligands.A patient-derived cytotoxic T-lymphocyte clone and two peptide-dependent monoclonal antibodies recognize HLA-B27-peptide complexes with low stringency for peptide sequences.Endogenous-peptide-dependent alloreactivity: new scientific insights and clinical implications.Availability of endogenous peptides limits expression of an M3a-Ld major histocompatibility complex class I chimera.Evolution of innate-like T cells and their selection by MHC class I-like molecules.Defective major histocompatibility complex class I expression on lymphoid cells in autoimmunity.Evidence for MR1 antigen presentation to mucosal-associated invariant T cells.Affinity maturation of lymphocyte receptors and positive selection of T cells in the thymus.Peptide dependency of alloreactive CD4+ T cell responses.Structure of HLA molecules and immunosuppressive effects of HLA derived peptides.Indirect T cell recognition in allograft rejection.Presentation without proteolytic cleavage of endogenous precursors in the MHC class I antigen processing pathway.Serum antibodies from patients with ankylosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Mycobacterium tuberculosis hsp60 gene.The interaction between beta 2-microglobulin (beta 2m) and purified class-I major histocompatibility (MHC) antigen.On the calculation of binding free energies using continuum methods: application to MHC class I protein-peptide interactions.Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide.Differential ability of isolated H-2 Kb subsets to serve as TCR ligands for allo-specific CTL clones: potential role for N-linked glycosylation.
P2860
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P2860
Peptide-induced conformational changes in class I heavy chains alter major histocompatibility complex recognition.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Peptide-induced conformational ...... atibility complex recognition.
@ast
Peptide-induced conformational ...... atibility complex recognition.
@en
type
label
Peptide-induced conformational ...... atibility complex recognition.
@ast
Peptide-induced conformational ...... atibility complex recognition.
@en
prefLabel
Peptide-induced conformational ...... atibility complex recognition.
@ast
Peptide-induced conformational ...... atibility complex recognition.
@en
P2093
P2860
P356
P1476
Peptide-induced conformational ...... atibility complex recognition.
@en
P2093
P2860
P304
P356
10.1084/JEM.176.6.1757
P407
P577
1992-12-01T00:00:00Z