Expression of simian virus 40 large T (tumor) oncogene in mouse chondrocytes induces cell proliferation without loss of the differentiated phenotype.
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P1343
A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen geneDisruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse modelUcma, a novel secreted cartilage-specific protein with implications in osteogenesisKnockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafishDedifferentiated chondrocytes cultured in alginate beads: restoration of the differentiated phenotype and of the metabolic responses to interleukin-1beta.Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes.Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigenHuman COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development.Controlled conversion of an immortalized mesodermal progenitor cell towards osteogenic, chondrogenic, or adipogenic pathways.SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen geneThe inhibition of cultured myoblast differentiation by the simian virus 40 large T antigen occurs after myogenin expression and Rb up-regulation and is not exerted by transformation-competent cytoplasmic mutants.NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism.Human immortalized chondrocytes carrying heterozygous FGFR3 mutations: an in vitro model to study chondrodysplasias.Differential effects of osteogenic protein-1 (BMP-7) on gene expression of BMP and GDF family members during differentiation of the mouse MC615 chondrocyte cells.Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox-9 transcription factor.Establishment and characterization of chondrocyte cell lines from the costal cartilage of SV40 large T antigen transgenic mice.Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1beta.Analysis of transcription of the Col6a1 gene in a specific set of tissues suggests a new variant of enhancer region.Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha.Immortalized, cloned mouse chondrocytic cells (MC615) produce three different matrix proteoglycans with core-protein-specific chondroitin/dermatan sulphate structures.Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene.Effects of [3H]glucosamine concentration on [3H]chondroitin sulphate formation by cultured chondrocytes.Proliferative potential and differentiated characteristics of cultured cardiac muscle cells expressing the SV40 T oncogene.Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo.Chronic exposure of bone morphogenetic protein-2 favors chondrogenic expression in human articular chondrocytes amplified in monolayer cultures.
P2860
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P2860
Expression of simian virus 40 large T (tumor) oncogene in mouse chondrocytes induces cell proliferation without loss of the differentiated phenotype.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Expression of simian virus 40 ...... the differentiated phenotype.
@ast
Expression of simian virus 40 ...... the differentiated phenotype.
@en
type
label
Expression of simian virus 40 ...... the differentiated phenotype.
@ast
Expression of simian virus 40 ...... the differentiated phenotype.
@en
prefLabel
Expression of simian virus 40 ...... the differentiated phenotype.
@ast
Expression of simian virus 40 ...... the differentiated phenotype.
@en
P2860
P356
P1476
Expression of simian virus 40 ...... the differentiated phenotype.
@en
P2093
F Mallein-Gerin
P2860
P304
P356
10.1073/PNAS.90.8.3289
P407
P4510
P577
1993-04-01T00:00:00Z