NAC covers ribosome-associated nascent chains thereby forming a protective environment for regions of nascent chains just emerging from the peptidyl transferase center.
about
A ribosome-associating factor chaperones tail-anchored membrane proteinsThe chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregationThe Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality ControlCrystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its αNAC subunitOM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria.The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo.The nascent polypeptide-associated complex (NAC) of yeast functions in the targeting process of ribosomes to the ER membrane.The molecular chaperone Ssb from Saccharomyces cerevisiae is a component of the ribosome-nascent chain complex.L25 functions as a conserved ribosomal docking site shared by nascent chain-associated complex and signal-recognition particle.The alpha and beta subunit of the nascent polypeptide-associated complex have distinct functionsDrugging the cancer kinome: progress and challenges in developing personalized molecular cancer therapeuticsA dual function for chaperones SSB-RAC and the NAC nascent polypeptide-associated complex on ribosomesThe nascent-polypeptide-associated complex: having a "NAC" for fidelity in translocation.Ribosome release factor RF4 and termination factor RF3 are involved in dissociation of peptidyl-tRNA from the ribosome.Divergent functional properties of the ribosome-associated molecular chaperone Ssb compared with other Hsp70s.Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes.Dual binding mode of the nascent polypeptide-associated complex reveals a novel universal adapter site on the ribosome.The nascent polypeptide-associated complex is essential for autophagic flux.Inhibition of a basal transcription factor 3-like gene Osj10gBTF3 in rice results in significant plant miniaturization and typical pollen abortion.Birth, life and death of nascent polypeptide chains.Translation elongation regulates substrate selection by the signal recognition particle.Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiaeAssembly of recently translated full-length and C-terminal truncated human gamma-globin chains with a pool of alpha-globin chains to form Hb F in a cell-free systemChaperone-assisted folding of newly synthesized proteins in the cytosol.Dual recognition of the ribosome and the signal recognition particle by the SRP receptor during protein targeting to the endoplasmic reticulum.The interaction of the chaperonin tailless complex polypeptide 1 (TCP1) ring complex (TRiC) with ribosome-bound nascent chains examined using photo-cross-linkingA general mechanism for regulation of access to the translocon: competition for a membrane attachment site on ribosomesSignal recognition particle-dependent targeting of ribosomes to the rough endoplasmic reticulum in the absence and presence of the nascent polypeptide-associated complex.Nascent polypeptide-associated complex stimulates protein import into yeast mitochondria.Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination.Fidelity of cotranslational protein targeting by the signal recognition particle.Cotranslational folding of globin.Exploring the roles of basal transcription factor 3 in eukaryotic growth and development.Co-translational mechanisms of quality control of newly synthesized polypeptides.Hold on to your friends: Dedicated chaperones of ribosomal proteins: Dedicated chaperones mediate the safe transfer of ribosomal proteins to their site of pre-ribosome incorporation.Mechanism of polypeptide translocation into the endoplasmic reticulum.Early encounters of a nascent membrane protein: specificity and timing of contacts inside and outside the ribosome.Structural conservation of the isolated zinc site in archaeal zinc-containing ferredoxins as revealed by x-ray absorption spectroscopic analysis and its evolutionary implications.Insertion and glycosylation of Pf3-derived membrane proteins in microsomes.αβ'-NAC cooperates with Sam37 to mediate early stages of mitochondrial protein import.
P2860
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P2860
NAC covers ribosome-associated nascent chains thereby forming a protective environment for regions of nascent chains just emerging from the peptidyl transferase center.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
NAC covers ribosome-associated ...... e peptidyl transferase center.
@ast
NAC covers ribosome-associated ...... e peptidyl transferase center.
@en
type
label
NAC covers ribosome-associated ...... e peptidyl transferase center.
@ast
NAC covers ribosome-associated ...... e peptidyl transferase center.
@en
prefLabel
NAC covers ribosome-associated ...... e peptidyl transferase center.
@ast
NAC covers ribosome-associated ...... e peptidyl transferase center.
@en
P2093
P2860
P356
P1476
NAC covers ribosome-associated ...... e peptidyl transferase center.
@en
P2093
P2860
P304
P356
10.1083/JCB.130.3.519
P407
P577
1995-08-01T00:00:00Z