The excitatory amino acid transporters: pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes.
about
Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationMechanisms of glutamate transportEngineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acidsQuantal glutamate release is essential for reliable neuronal encodings in cerebral networksLigand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual ScreeningFunctional roles of high-affinity glutamate transporters in cochlear afferent synaptic transmission in the mouse.Functional expression, purification and high sequence coverage mass spectrometric characterization of human excitatory amino acid transporter EAAT2Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis.Glutamate as a neurotransmitter in the healthy brainbeta-Lactam antibiotic inhibits development of morphine physical dependence in rats.System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.[(18)F](2S,4S)-4-(3-Fluoropropyl)glutamine as a tumor imaging agent.The cystine/glutamate antiporter regulates dendritic cell differentiation and antigen presentationα7 Nicotinic Receptor Promotes the Neuroprotective Functions of Astrocytes against Oxaliplatin NeurotoxicityDefining substrate and blocker activity of alanine-serine-cysteine transporter 2 (ASCT2) Ligands with Novel Serine AnalogsAcidosis-Induced Dysfunction of Cortical GABAergic Neurons through Astrocyte-Related Excitotoxicity.Engaging neuroscience to advance translational research in brain barrier biology.Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes.Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement.Regional distribution of sodium-dependent excitatory amino acid transporters in rat spinal cordThe role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention.Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro.Astrocytes--friends or foes in multiple sclerosis?Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels.The four major N- and C-terminal splice variants of the excitatory amino acid transporter GLT-1 form cell surface homomeric and heteromeric assemblies.Toward a new role for plasma membrane sodium-dependent glutamate transporters of astrocytes: maintenance of antioxidant defenses beyond extracellular glutamate clearance.GLAST But Not Least--Distribution, Function, Genetics and Epigenetics of L-Glutamate Transport in Brain--Focus on GLAST/EAAT1.Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease.Lens glutathione homeostasis: Discrepancies and gaps in knowledge standing in the way of novel therapeutic approaches.Family-based association testing of glutamate transporter genes in autism.Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms.Synthesis and preliminary pharmacological evaluation of novel derivatives of L-beta-threo-benzylaspartate as inhibitors of the neuronal glutamate transporter EAAT3Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter.Functional and morphological characterization of glutamate transporters in the rat locus coeruleus.Unexpected Formation of Highly Functionalized Dihydropyrans via Addition-Cyclization Reactions Between Dimethyl Oxoglutaconate and α,β-Unsaturated Hydrazones.Chemoenzymatic Synthesis of ortho-, meta-, and para-Substituted Derivatives of l-threo-3-Benzyloxyaspartate, An Important Glutamate Transporter Blocker.Antinociceptive effect of clavulanic acid and its preventive activity against development of morphine tolerance and dependence in animal models.The glutamate aspartate transporter (GLAST) mediates L-glutamate-stimulated ascorbate-release via swelling-activated anion channels in cultured neonatal rodent astrocytes.Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine.A sequential impairment of cortical astrocytes and GABAergic neurons during ischemia is improved by mGluR₁,₅ activation.
P2860
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P2860
The excitatory amino acid transporters: pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@ast
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@en
type
label
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@ast
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@en
prefLabel
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@ast
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@en
P1476
The excitatory amino acid tran ...... cificity of the EAAT subtypes.
@en
P2093
C Sean Esslinger
Richard J Bridges
P304
P356
10.1016/J.PHARMTHERA.2005.01.002
P577
2005-04-14T00:00:00Z