Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. - Wikidata - awgldk - TriplyDB

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.

http://www.wikidata.org/entity/Q36236484

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New perspectives in glioblastoma antiangiogenic therapy ROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic Strategies Clinical management of grade III oligodendroglioma Spinal cord tumours: advances in genetics and their implications for treatment Molecular characteristics of pediatric high-grade gliomas New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma Modern brain tumor imaging Oligodendroglioma: pathology, molecular mechanisms and markers Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.Molecular heterogeneity in glioblastoma: potential clinical implications Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells Mutational landscape and significance across 12 major cancer types Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification The epidemiology of glioma in adults: a "state of the science" review Epidemiologic and molecular prognostic review of glioblastoma Telomere length and risk of glioma Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors Survival and low-grade glioma: the emergence of genetic information The mutational landscape of chromatin regulatory factors across 4,623 tumor samples.Big data visualization identifies the multidimensional molecular landscape of human gliomas.Recent advances in subtyping tumors of the central nervous system using molecular data.Histone variants: emerging players in cancer biology.The genetic landscape of anaplastic astrocytoma.Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Molecular Testing of Brain Tumor.Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and science ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples samples.Actionable molecular biomarkers in primary brain tumors.Quantitative iTRAQ LC-MS/MS Proteomics Reveals Transcription Factor Crosstalk and Regulatory Networks in Hypopharyngeal Squamous Cell Carcinoma Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.Genetic landscape of extreme responders with anaplastic oligodendroglioma.Imaging growth and isocitrate dehydrogenase 1 mutation are independent predictors for diffuse low-grade gliomas.Mutant IDH1-driven cellular transformation increases RAD51-mediated homologous recombination and temozolomide resistance.Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma.Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma Telomere maintenance mechanisms in cancer: clinical implications TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations.

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Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.

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Frequent ATRX, CIC, FUBP1 and ...... fication of malignant gliomas.

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Frequent ATRX, CIC, FUBP1 and ...... fication of malignant gliomas.

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Frequent ATRX, CIC, FUBP1 and ...... fication of malignant gliomas.

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Ahmed B Rasheed

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Alan K Meeker

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Chetan Bettegowda

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Christopher M Heaphy

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Christopher Pirozzi

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Fausto J Rodriguez

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Giselle Lopez

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Gregory J Riggins

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Hai Yan

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Matthias Holdhoff

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P2860

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

The 2007 WHO classification of tumours of the central nervous system

Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin

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709-722

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10.18632/ONCOTARGET.588

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3

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Kenneth W Kinzler

Luis Alberto Diaz Jr

Darell D. Bigner

Henry Seth Friedman

Bert Vogelstein

Roger E McLendon

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2012-07-01T00:00:00Z

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230623548

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22869205

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