Relevance of PTEN loss in brain metastasis formation in breast cancer patients - Wikidata - awgldk - TriplyDB

Relevance of PTEN loss in brain metastasis formation in breast cancer patients

Relevance of PTEN loss in brain metastasis formation in breast cancer patients

http://www.wikidata.org/entity/Q36245550

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Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context.Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells Melittin restores PTEN expression by down-regulating HDAC2 in human hepatocelluar carcinoma HepG2 cells.Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.The molecular genomics of metastatic brain tumours.miR-20b is up-regulated in brain metastases from primary breast cancers PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo.Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics.Organ-specific isogenic metastatic breast cancer cell lines exhibit distinct Raman spectral signatures and metabolomes.MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis EGFR and HER2 signaling in breast cancer brain metastasis.Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases.Breast cancer metastasis: issues for the personalization of its prevention and treatment.PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression.Biology, detection, and clinical implications of circulating tumor cells.Systemic therapy of brain metastases.Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.Restoration of PTEN activity decreases metastases in an orthotopic model of colon cancer.Genetic Characterization of Brain Metastases in the Era of Targeted Therapy.Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women.Cytokeratin 5/6, c-Met expressions, and PTEN loss prognostic indicators in triple-negative breast cancer.Metabolic advantages and vulnerabilities in brain metastases.Predicting and Overcoming Chemotherapeutic Resistance in Breast Cancer.Drug resistance in HER2-positive breast cancer brain metastases: blame the barrier or the brain?[Tumor Cells and Micro-environment in Brain Metastases].Breast cancer brain metastasis: molecular mechanisms and directions for treatment

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

http://www.wikidata.org/entity/Q36245550

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2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Breast Cancer Research

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Christian Benner

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Dirk Kemming

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Guido Sauter

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Ina Hohensee

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Kathrin Eylmann

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Katrin Lamszus

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Klaus Pantel

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Liubov Uslar

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Manfred Westphal

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Michaela Wrage

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P2860

Genes that mediate breast cancer metastasis to the brain

Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis

Human and mouse oligonucleotide-based array CGH.

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation.

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

Genome remodelling in a basal-like breast cancer metastasis and xenograft

A molecular signature of metastasis in primary solid tumors

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions.

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