Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors.
about
A novel combination of K-ras and myc amplification accompanied by point mutational activation of K-ras in a human lung cancermyc protooncogene linked to retroviral promoter, but not to enhancer, transforms embryo cells.Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript.Transformation of quail embryo fibroblasts by a retrovirus carrying a normal human c-myc geneAvian proto-myc genes promoted by defective or nondefective retroviruses are single-hit transforming genes in primary cells.The genome of the chicken DT40 bursal lymphoma cell line.c-myc hypermutation in Burkitt's lymphoma.Enhanced c-Ki-ras expression associated with Friend virus integration in a bone marrow-derived mouse cell line.Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.Retroviral insertional mutagenesis: past, present and future.Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoterAbsence of missense mutations in activated c-myc genes in avian leukosis virus-induced B-cell lymphomasAn avian retrovirus expressing chicken pp59c-myc possesses weak transforming activity distinct from v-myc that may be modulated by adjacent normal cell neighbors.cis-acting regulatory elements within gag genes of avian retroviruses.Definition of regions in human c-myc that are involved in transformation and nuclear localization.A new pathway in the generation of defective retrovirus DNAPatterns of proviral insertion and deletion in avian leukosis virus-induced lymphomasCloning and sequencing of a c-myc oncogene in a Burkitt's lymphoma cell line that is translocated to a germ line alpha switch region.Recombination events after transient infection and stable integration of DNA into mouse cells.An aberrant avian leukosis virus provirus inserted downstream from the chicken c-myc coding sequence in a bursal lymphoma results from intrachromosomal recombination between two proviruses and deletion of cellular DNAB-lymphoma induction by reticuloendotheliosis virus: characterization of a mutated chicken syncytial virus provirus involved in c-myc activation.High-frequency transduction of c-erbB in avian leukosis virus-induced erythroblastosis.Insertional activation of c-myc by reticuloendotheliosis virus in chicken B lymphoma: nonrandom distribution and orientation of the provirusesNucleotide sequence of a transduced myc gene from a defective feline leukemia provirus.Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53, or normal c-myc genes5' long terminal repeats of myc-associated proviruses appear structurally intact but are functionally impaired in tumors induced by avian leukosis viruses.Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene.Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene.Nucleotide sequence 5' of the chicken c-myc coding region: localization of a noncoding exon that is absent from myc transcripts in most avian leukosis virus-induced lymphomasActivation of a translocated c-myc gene: role of structural alterations in the upstream region.Nucleotide sequence of two overlapping myc-related genes in avian carcinoma virus OK10 and their relation to the myc genes of other viruses and the cell.A common functional consequence of tumor-derived mutations within c-MYC.A conditional self-inactivating retrovirus vector that uses a tetracycline-responsive expression system.Improved self-inactivating retroviral vectors derived from spleen necrosis virus.gag as well as myc sequences contribute to the transforming phenotype of the avian retrovirus FH3.Sequences outside of the long terminal repeat determine the lymphomogenic potential of Rous-associated virus type 1.(A-T)n tracts embedded in random sequence DNA--formation of a structure which is chemically reactive and torsionally deformable.A retroviral provirus closely associated with the Ren-2 gene of DBA/2 mice.Functional analysis of the transcription control region located within the avian retroviral long terminal repeat.Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas.
P2860
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P2860
Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh
1984年學術文章
@zh-hant
name
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@ast
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@en
type
label
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@ast
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@en
prefLabel
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@ast
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@en
P2860
P356
P1476
Proviral deletions and oncogen ...... ession of avian bursal tumors.
@en
P2093
P2860
P304
P356
10.1073/PNAS.81.3.843
P407
P577
1984-02-01T00:00:00Z