Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment - Wikidata - awgldk - TriplyDB

Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

http://www.wikidata.org/entity/Q36255234

about

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein Rab7A is required for efficient production of infectious HIV-1 Human VPS34 and p150 are Rab7 interacting partners Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate Structural basis for recruitment of RILP by small GTPase Rab7 Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion Rab22a regulates the recycling of membrane proteins internalized independently of clathrin Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells Rabring7, a novel Rab7 target protein with a RING finger motif Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression Multiple Roles of the Small GTPase Rab7 Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis Mannose 6-phosphate receptors: new twists in the tale Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7.Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport Rab7: a key to lysosome biogenesis Missense mutations in the SH3TC2 protein causing Charcot-Marie-Tooth disease type 4C affect its localization in the plasma membrane and endocytic pathway.Protein networks supporting AP-3 function in targeting lysosomal membrane proteins.The Salmonella effector PipB2 affects late endosome/lysosome distribution to mediate Sif extension.Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.Transport to late endosomes is required for efficient reovirus infection Pharmacogenomic analysis: correlating molecular substructure classes with microarray gene expression data.Expression of rab11a N124I in gastric parietal cells inhibits stimulatory recruitment of the H+-K+-ATPase.Phylogeny and evolution of Rab7 and Rab9 proteins Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes.Mycobacterium tuberculosis phagosome.

P2860

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P2860

Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

http://www.wikidata.org/entity/Q36255234

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年學術文章

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1998年學術文章

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1998年學術文章

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name

Mutant Rab7 causes the accumul ...... an early endocytic compartment

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Mutant Rab7 causes the accumul ...... an early endocytic compartment

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type

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Mutant Rab7 causes the accumul ...... an early endocytic compartment

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Mutant Rab7 causes the accumul ...... an early endocytic compartment

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prefLabel

Mutant Rab7 causes the accumul ...... an early endocytic compartment

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Mutant Rab7 causes the accumul ...... an early endocytic compartment

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Mutant Rab7 causes the accumul ...... an early endocytic compartment

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P2093

A Wandinger-Ness

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B Hoflack

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B Press

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Y Feng

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P2860

AP-3: an adaptor-like protein complex with ubiquitous expression.

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane

Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

Mannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGN

Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus

The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance.

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1075-1089

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5

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140

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9490721

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2132709

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