Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration.
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Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotypeDirect binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signalingCortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.Activation of glial FGFRs is essential in glial migration, proliferation, and survival and in glia-neuron signaling during olfactory system developmentInhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical applicationStimulation of DNA synthesis and cell proliferation of human mammary myoepithelial-like cells by hepatocyte growth factor/scatter factor depends on heparan sulfate proteoglycans and sustained phosphorylation of mitogen-activated protein kinases p42/Alterations in cell-adhesive and migratory properties of proximal tubule and collecting duct cells from bcl-2 -/- miceFGF-1-induced reactions for biogenesis of apoE-HDL are mediated by src in rat astrocytesAmlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitroATF-1 mediates protease-activated receptor-1 but not receptor tyrosine kinase-induced DNA synthesis in vascular smooth muscle cellsSignaling from fibroblast growth factor receptor 2 in immature hematopoietic cells facilitates donor hematopoiesis after intra-bone marrow-bone marrow transplantationSrc family kinases are required for integrin but not PDGFR signal transduction.The mitogenic signaling pathway for fibroblast growth factor-2 involves the tyrosine phosphorylation of cyclin D2 in MCF-7 human breast cancer cells.Inhibition of angiogenesis by a mouse sprouty protein.Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor.Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway.Fibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway.A new hypothesis for the cancer mechanism.NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1).Relevance of partially structured states in the non-classical secretion of acidic fibroblast growth factor.Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.Current status of SRC inhibitors in solid tumor malignancies.Ligands to FGF receptor 2-IIIb induce proliferation, motility, protection from cell death and cytoskeletal rearrangements in epithelial ovarian cancer cell lines.Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.Cooperative roles of Fyn and cortactin in cell migration of metastatic murine melanoma.The nonreceptor protein-tyrosine kinase c-Fes is involved in fibroblast growth factor-2-induced chemotaxis of murine brain capillary endothelial cells.Binding of factor VIIa to tissue factor on keratinocytes induces gene expression.Signaling within a caveolae-like membrane microdomain in human neuroblastoma cells in response to fibroblast growth factor.Thrombin induces rapid PAR1-mediated non-classical FGF1 release.Signal transducers and activators of transcription mediate fibroblast growth factor-induced vascular endothelial morphogenesis.ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation.Src is required for cell migration and shape changes induced by fibroblast growth factor 1.Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor.Reciprocal antagonism coordinates C-type natriuretic peptide and mitogen-signaling pathways in fibroblasts.Keratinocyte growth factor activates p38 MAPK to induce stress fibre formation in human prostate DU145 cells.FGF-1 and FGF-2 regulate the expression of E-cadherin and catenins in pancreatic adenocarcinoma.Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent.Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
P2860
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P2860
Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Activation of the MAP kinase p ...... way correlates with migration.
@ast
Activation of the MAP kinase p ...... way correlates with migration.
@en
type
label
Activation of the MAP kinase p ...... way correlates with migration.
@ast
Activation of the MAP kinase p ...... way correlates with migration.
@en
prefLabel
Activation of the MAP kinase p ...... way correlates with migration.
@ast
Activation of the MAP kinase p ...... way correlates with migration.
@en
P2093
P2860
P356
P1476
Activation of the MAP kinase p ...... way correlates with migration.
@en
P2093
P2860
P304
P356
10.1083/JCB.141.7.1647
P407
P577
1998-06-01T00:00:00Z