Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway.
about
Inhibitors of MAO-A and MAO-B in Psychiatry and NeurologyChemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary cultureNew Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy.Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugsHow to optimize the treatment of early stage Parkinson's disease.Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and β-amyloid in ageing and Alzheimer's disease.Transcriptional landscapes at the intersection of neuronal apoptosis and substance P-induced survival: exploring pathways and drug targets.Protein kinase Cepsilon: the mitochondria-mediated signaling pathway.α-Tocopherol at Nanomolar Concentration Protects Cortical Neurons against Oxidative Stress.The role of rasagiline in the treatment of Parkinson's disease.The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's diseaseMilestones in Parkinson's disease therapeutics.Explaining ADAGIO: a critical review of the biological basis for the clinical effects of rasagiline.Designing drugs with multi-target activity: the next step in the treatment of neurodegenerative disorders.Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression.Rasagiline and rapid symptomatic motor effect in Parkinson's disease: review of literature.Rasagiline in treatment of Parkinson's disease.C-terminal mechano-growth factor induces heme oxygenase-1-mediated neuroprotection of SH-SY5Y cells via the protein kinase Cϵ/Nrf2 pathway.Early Parkinson's disease patients on rasagiline present with better odor discrimination.Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.Neurotrophic function of phytochemicals for neuroprotection in aging and neurodegenerative disorders: modulation of intracellular signaling and gene expression.Effects of rasagiline on olfactory function in patients with Parkinson’s disease.No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice.Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson's disease therapeutic agents in MPP+ and rotenone models.Biocatalysis, DNA-protein interactions, cytotoxicity and molecular docking of Cu(II), Ni(II), Zn(II) and V(IV) Schiff base complexes
P2860
Q28069609-6F109CCE-1321-48E4-8B04-A62ECA9F672BQ28475734-F8FDD3F2-F995-4D68-B5BA-6C460875CCCBQ33783000-70DC3004-BCBA-4948-B019-8A23A4691DB1Q34725080-815BB64A-3F8B-4071-82DB-63EA0C006FD8Q34911093-794BDE19-19F8-4E3D-A5E5-04DD5B0650EDQ35599297-B5ED957F-B784-43AD-A319-E6486EF00D5FQ37005143-50377BA5-1EF3-4647-8437-55ED46C93C32Q37164298-CE369B9B-7F23-43C5-A253-034BC96CCF07Q37219736-20688446-0D10-4F39-9CDB-250D936D9E8FQ37631713-AAC7CB6F-461D-4E51-B532-ADDC37F66A6AQ37762167-0FA0AAC9-4B8D-4EEE-A139-5234EE94A648Q37845675-B276427D-1A9D-4B0C-A7BD-6BF21218B758Q37882596-1D2D3749-6804-44B6-8243-B41E6456CB42Q37939755-8C434C6F-14B7-45FD-B05D-EF9F48633480Q38066606-5CAE1464-CE9D-4EFC-B69B-4E3E15D5DD7CQ38325601-AEE15089-348D-4ED8-9837-FC9E8CCF077BQ38497529-A715463A-A481-44CC-B627-B8DE741ABE12Q39315311-35A6B783-12E1-4B72-A884-3D2187EFCAA7Q39603952-99BC28FF-39FC-41D4-85C2-B22C5983F460Q40680514-EBF6B4BD-31D6-4506-9AAF-F2C687B463C5Q42573791-5D19F796-A341-4B68-90E4-5477D8357C04Q48019570-FF29ABC7-178A-4B6E-9D74-DC152762DEB6Q48140409-8C6A9478-F952-428D-B6C3-8CB7A15B3E47Q48343609-B9D34F3D-FDF0-4C91-95E5-EEE24AE03295Q52750366-1C383BA2-8C7A-4748-A3B7-DAB789046A09Q57816439-61A75395-1B8C-4CDB-ABFD-5E9EE980CE99
P2860
Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@ast
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@en
type
label
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@ast
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@en
prefLabel
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@ast
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@en
P2093
P356
P1476
Novel neuroprotective mechanis ...... mily members with PKC pathway.
@en
P2093
Moussa B H Youdim
Orit Bar-Am
Orly Chillag-Talmor
Orly Weinreb
Tamar Amit
P304
P356
10.1196/ANNALS.1344.030
P407
P577
2005-08-01T00:00:00Z